The 49ers signed veteran defensive tackles Tony McDaniel and Leger Douzable, the team announced.
The 49ers placed defensive lineman Arik Armstead in injured reserve with a broken hand and released veteran tight end Logan Paulsen to make room for McDaniel and Douzable on the 53-man roster.
Armstead, who is scheduled to undergo surgery for a broken hand. Armstead was placed on injured reserve Tuesday and is not expected back for approximately two months.
Paulsen was used primarily as a blocking tight end. He saw action in the 49ers' first six games and did not catch a pass. The 49ers promoted undrafted rookie tight end Cole Hikutini to the active roster on Saturday.
McDaniel, 32, has not appeared in an NFL game this season after starting 10 of the 16 games in which he played last season with the Seattle Seahawks. In his 12-year career, McDaniel has played for Jacksonville, Miami, Seattle, Tampa Bay and, again, Seattle. He has recorded 11.5 career sacks.
Douzable was among the team's final cuts before the start of the regular season. An eight-year veteran, Douzable has seen action with the Giants, Rams, Jaguars, Jets and Bills.