Left-hander Eduardo Rodriguez is on the mound for the Red Sox with Sandy Leon catching in the second game of the three-game series in Minnesota on Saturday (2:05 p.m.).
The Red Sox won 8-1 on Friday night at Target Field.
In his third start of the season since coming off the disabled list, Rodriguez (1-1, 5.40 ERA) will try to bounce back from his outing on Sunday in which he allowed four homers in six innings in a 5-4 loss to Toronto at Fenway Park. Leon was called up from Triple-A Pawtucket earlier this week when Ryan Hanigan was placed on the 15-day DL with a neck injury.
Right-hander Kyle Gibson (0-3, 6.10) is on the mound for the Twins.
The lineups:
RED SOX
Mookie Betts RF
Dustin Pedroia 2B
Xander Bogaerts SS
David Ortiz DH
Hanle Ramirez 1B
Jackie Bradley Jr. CF
Chris Young LF
Travis Shaw 3B
Sandy Leon C
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Eduardo Rodriguez LHP
TWINS
Eduardo Nunez SS
Joe Mauer DH
Robbie Grossman LF
Trevor Plouffe 3B
Brian Dozier 2B
Byung Ho Park 1B
Max Kepler RF
Kurt Suzuki C
Byron Buxton CF
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Kyle Gibson RHP