FOXBORO -- The Patriots will be without two of their most effective down-the-field receiving threats when they take on the 49ers this Sunday.
Both tight end Rob Gronkowski and receiver Chris Hogan have been ruled out for the game as they continue to deal with their injuries. Gronkowski is managing a chest ailment, while Hogan suffered a back issue before last week's game with the Seahawks. Hogan played in the game but did not register a catch.
Patriots tight end Martellus Bennett (ankle) and receiver Julian Edelman (foot) are both questionable headed into the game.
With Gronkowski out, the Patriots could lean on Bennett more heavily in the passing game. Hogan's absence should mean more work for receivers Malcolm Mitchell and Danny Amendola.
Running back Dion Lewis, who has yet to play in a regular-season game after starting the season on the physically unable to perform list, has made the trip to San Francisco.