Karekin Brooks had 10 carries for 142 yards and two touchdowns to help Pennsylvania beat Division II Ohio Dominican 42-24 on Saturday in the Quakers' season opener.
Will Fischer-Colbrie threw for 198 yards and two scores, and Justin Watson had eight receptions for 134 yards and two touchdowns.
On the first drive of the third quarter, Fischer-Colbrie threw for a 2-yard score to Watson to cap a 7-play, 65-yard drive, giving to Penn the lead for good at 14-10. Three-plus minutes later, Brooks scored from 18-yards out to make it 21-10 and Nicholas Bokun scored on a 30-yard reception at the 6:12 mark for an 18-point lead.
Grant Russell threw for 273 yards and two scores for Old Dominican (0-3).
The Panthers took an early 7-0 lead on Cedric Washington's 40-yard touchdown reception with 9:22 left in the first quarter to cap a seven-play, 79-yard drive.
The Quakers played their 1,374th game, the most of any program at any level of college football.
NEW YORK — Josh Wainwright caught 10 passes for 193 yards and two touchdowns, including a 24-yarder from Anders Hill in overtime, and Columbia defeated Pennsylvania 34-31 on Saturday for its best start since 1996.
The Lions (5-0, 2-0 Ivy) knocked off the defending Ivy League champions for the first time in 21 tries and snapped an 11-game home skid against the Quakers (2-3, 0-2). The Lions are assured of no worse than a .500 record after winning just five games in its last four seasons.
Penn appeared to be in control after Nick Miller's 25-yard interception return gave the Quakers a 21-7 lead in the third quarter. But the Lions rallied for three TDs in the fourth to take a 28-21 lead. Josh Bean started the Columbia scoring with a 1-yard plunge. Hill hit Wainwright for a 59-yard score to knot the score at 21 and then connected with Rory Schlageter from 7 yards out for the go-ahead score.
The Quakers sent the game to overtime on Will Fischer-Colbrie's 17-yard scoring strike to Justin Watson with 1:21 left. Penn got the ball first in OT, but settled for a 41-yard field goal. The Lions faced a third-and-9 when Hill hooked up with Wainwright for the game-winner.
Hill finished with 258 yards on 21-of-33 passing with three TDs and an interception.
Fischer-Colbrie completed 14 of 25 passes for 186 yards and a score. He threw two interceptions.
NEW BRITAIN, Conn. -- Najae Brown returned an interception 79 yards for a touchdown and Central Connecticut scored five more on offense to defeat Penn 42-21 on Saturday.
The Blue Devils (3-3) rolled up 473 yards of total offense -- Jake Dolegala passed for 179 yards and scrambled for another 15 and a touchdown. Dolegala also found Drew Jean-Guillaume for a 7-yard touchdown pass before halftime. Central Connecticut rushed for 294 yards on 53 carries and four scores. Jean-Guillame opened the game with a TD run from the 14, Courtney Rush and Cameron Nash had scoring runs of 8 and 1 yards, respectively.
Brown picked off Nick Robinson and returned it 79 yards to give the Blue Devils an early 21-0 lead.
Penn came back on three Robinson touchdown passes -- to Christian Pearson and a pair to Justin Watson to pull within 28-21 with 18 seconds left in the first half. The Quakers (2-2) didn't score after halftime.