The Sixers (28-48) face the Toronto Raptors (46-30) at Air Canada Centre (6 p.m./CSN, CSNPhilly.com and the NBC Sports app).
Let's take a closer look at the matchup:
1. Dust yourself off
The Sixers walked -- or limped -- right into a buzzsaw their last time on the court.
Already shorthanded, the Sixers were dominated by the hungry Cleveland Cavaliers in a 122-105 loss Friday night. They allowed the Cavs to shoot 52.6 percent from the field, 44.8 percent from three-point range, grab 53 rebounds and score 54 points in the paint.
"I think they played at a championship level," Brett Brown said. "They took their frustrations out on us."
2. The new guys
The Sixers now get to square off against another team attempting to round into postseason form in the Raptors.
Even with point guard Kyle Lowry sidelined after undergoing wrist surgery, the Raptors have managed to maintain their solid play. They are 13-6 since Lowry went down near the end of February.
That has a lot to do with the play of newcomers Serge Ibaka and P.J. Tucker, who were acquired at the trade deadline.
Since coming over from Orlando, Ibaka has had the bigger impact numbers-wise. He's averaged 14.7 points, 6.7 rebounds and 1.3 blocks with the Raptors.
Tucker has put up 5.9 points and 5.5 rebounds since coming aboard, but his value has been primarily as a lockdown defender.
3. Walk the line
A big difference maker in the season series between the Sixers and Raptors has been the free-throw line.
The Raptors, who rank top 10 in the NBA in free throws attempted, free throws made and free-throw percentage, owned the charity stripe in the first two clashes. Toronto shot 25 of 31 from the line in the first matchup and 31 of 36 in the second.
On the other side, the Sixers were 28 for 38 combined at the line in the two games, both losses.
In the third matchup -- a 94-89 Sixers' win on Jan. 18 -- they were 24 of 32 at the stripe compared to 15 of 23 for the Raptors.
Robert Covington (knee), Sergio Rodriguez (hamstring), Jahlil Okafor (knee), Joel Embiid (knee), Ben Simmons (foot) and Jerryd Bayless (wrist) are out for the Sixers.
Lowry (wrist) is out for the Raptors.
5. This and that
• The Sixers snapped a 14-game losing skid to the Raptors with that Jan. 18 win.
• DeMar DeRozan has been right on his season scoring average with 27.6 points a night in the 19 games since Lowry went down. However, he has also reached the 40-point mark four times during that span, including in a 111-100 win over the Indiana Pacers on Friday.
• Canada native Nik Stauskas has struggled against the Raptors in 2016-17 with just 4.3 points per matchup, his second-lowest mark against any team this season.