Phillies manager Pete Mackanin will go with the same lineup for the second consecutive game after falling to the Nationals, 7-6, in the home opener Friday at Citizens Bank Park.
All eyes will be on starting pitcher Aaron Nola, who will start his first game of the season after suffering an elbow injury that cost him the second half of last season.
While Nola might be the focus of tonight's game, the Phillies will also hope to get some production from their players in the middle of the lineup.
Maikel Franco, Tommy Joseph, Michael Saunders and Cameron Rupp are a combined 5 for 50 through four games this season, but they might be able to get into a rhythm in the batter's box against Jeremy Guthrie, who posted a 5.95 ERA the last time he pitched in the majors with the Royals in 2015. He posted a 7.17 ERA in Triple-A last season.
Here's the Phillies' full lineup:
1. Cesar Hernandez, 2B
2. Howie Kendrick, LF
3. Odubel Herrera, CF
4. Maikel Franco, 3B
5. Michael Saunders, RF
6. Tommy Joseph, 1B
7. Cameron Rupp, C
8. Freddy Galvis, SS
9. Aaron Nola, P
And the Nationals' lineup:
MLB
1. Trea Turner, SS
2. Adam Eaton, CF
3. Bryce Harper, RF
4. Daniel Murphy, 2B
5. Ryan Zimmerman, 1B
6. Jayson Werth, LF
7. Anthony Rendon, 3B
8. Matt Wieters, C
9. Jeremy Guthrie, P
For more on tonight's game, check out Corey Seidman's game notes.