SAN FRANCISCO (AP) The New York Giants issued a statement of their own to 49ers coach Jim Harbaugh on Sunday.
Maybe the rest of the NFL, too.
While questions still surround the defending Super Bowl champions, New York's 26-3 rout of the favored 49ers sent a clear message across the league.
``The statement made,'' wide receiver Victor Cruz said, ``is that we're here to stay.''
Antrel Rolle intercepted two passes by Alex Smith, Prince Amukamara picked off another and the Giants shut down San Francisco in a rematch of last season's NFC championship game. After outscoring the Bills and Jets by a combined 79-3 the last two weeks, the 49ers (4-2) met their match again.
No overtime needed this time, and not much of Eli Manning, either.
Manning threw for 193 yards and one touchdown, Ahmad Bradshaw ran for 116 yards and a score and New York (4-2) rode that dominant defense and four field goals by Lawrence Tynes to hand the outspoken Harbaugh the most lopsided loss of his tenure.
What a San Francisco treat.
``We were just waiting for them to play like we know they can play,'' Manning said of New York's defense. ``They played outstanding. They played really well, flying around.''
The Giants grinded out a 20-17 overtime win at rain-soaked Candlestick Park on Jan. 22, capitalizing on two fumbles by fill-in punt returner Kyle Williams en route to another Super Bowl victory over the Patriots. All week, some San Francisco players talked about ``unfinished business.'' And Harbaugh added to the hype when he fired back a strongly worded statement criticizing Giants offensive coordinator Kevin Gilbride, who had mostly praised San Francisco and defensive end Justin Smith before saying the All-Pro often ``gets away with murder'' holding linemen.
Harbaugh issued a news release calling that an ``outrageous, irrational statement'' and said ``it's obvious that the Giants coaching staff's sole purpose is to use their high visibility to both criticize and influence officiating.''
For all the hoopla, the rematch was never close.
Amukamara's interception in the second quarter started a surge of New York offense. Smith, who wore tape around his sprained middle finger that he said wasn't an issue, lofted the pass too high and allowed Amukamara to leap underneath the ball before tight end Delanie Walker even had a chance at the Giants 33.
At one point in the first half, Manning completed eight consecutive passes for 142 yards and had the usually stout San Francisco defense out of sorts. Domenik Hixon tip-toed the sideline to catch passes of 39 and 16 yards on consecutive third downs, and Cruz followed with a 6-yard touchdown reception and his usual salsa dance in the end zone for a 7-3 lead.
``We know last year wasn't a fluke,'' Bradshaw said. ``We know what we can be.''
Tynes kicked a 34-yard field goal for a 10-3 lead and Tarell Brown blocked a 40-yard attempt by Tynes, which led to David Akers' miss wide left from 52 yards as the half expired.
Akers, who tied the NFL record with a 63-yard field goal in a Week 1 win at Green Bay, also hooked a 43-yarder wide right on San Francisco's first drive. He made a 42-yarder from the same right hash mark. The All-Pro kicker is 11 of 16 this season.
``It wasn't a great day for any of us,'' Harbaugh said.
Once the break was over, the Giants sent San Francisco spiraling down and out in a New York minute.
David Wilson returned the second-half kickoff 66 yards to set up Bradshaw's 1-yard TD run. That quieted the Candlestick crowd - except for the Giants fans that sprinkled the stands blue on a sun-splashed day along the bay.
The 49ers had not allowed a 100-yard rusher in the previous 22 home games. The last time was Tennessee's Chris Johnson, who ran for 135 yards on Nov. 8, 2009
On San Francisco's next two possessions, Rolle intercepted Smith's passes. The first came on an overthrown pass intended for former Giant Mario Manningham that Rolle returned 20 yards to the San Francisco 12. On the second, he stepped in front of a pass to Williams and ran 22 yards to the San Francisco 5.
``I could tell, at times, we had him a little rattled,'' Rolle said.
``It's tough to speak about any other facet,'' Smith said. ``We made it tough on the defense.''
The only downside for New York is it settled for field goals both times. Then again, not many points were needed.
The Giants sacked Smith six times and had him under constant pressure, made worse when left tackle Joe Staley left with a concussion in the third quarter. Smith finished 19 of 30 for 200 yards, and the 49ers were held to 80 yards rushing.
``The nice thing was the pounding away of the pencil on the defensive line,'' Giants coach Tom Coughlin said. ``I think the defensive line finally decided they were going to come out and play today and they did.''
The 49ers were coming off a 45-3 home romp against Buffalo, racking up a franchise-record 621 yards and becoming the first team in NFL history with 300 yards passing and 300 yards rushing in the same game. This time, they were smashed.
``Coaches always let us know that we're not the kings of the NFL, the Giants are,'' 49ers cornerback Carlos Rogers said. ``They won a title last year and they're still that team to beat until somebody wins the Super Bowl.''
NOTES: San Francisco's 16-6 loss at the Baltimore Ravens last Thanksgiving night had been the most lopsided defeat the last two seasons. ... It was the seventh time in Smith's career the 2005 No. 1 overall pick threw three interceptions and first since a 27-13 loss at Philadelphia on Dec. 20, 2009. ... 49ers RB Brandon Jacobs, who was inactive again, was in the Giants locker room handing out hugs and handshakes after the game to his former teammates.
Antonio Gonzalez can be reached at: www.twitter.com/agonzalezAP