Here are the best Week 6 waiver wire pickups for NFL fantasy football.
Bye week: Dak Prescott, Russell Wilson, Andy Dalton, Tyrod Taylor
Jacoby Brissett -- Not a great pool of options for those in need this week, but the Colts starter looks like the best bet. Indianapolis faces a Tennessee defense allowing the fourth-most points to fantasy quarterbacks and the most touchdown passes (tied with New England). Brissett put up solid points in recent games and he'll provide some help with his legs. Not bad for beggars can't be choosers scenario.
Case Keenum -- Shrugs. Pick Josh McCown at home against the Patriots or Brian Hoyer against a Redskins defense without Josh Norman if you want. Of these three, I'll lean Keenum because 1) He has the best receiving weapons with Stefon Diggs, Adam Thielen, Kyle Rudolph and 2) the likelihood of having to play catch up or at least keep up against Green Bay's Aaron Rodgers.
Be concerned: Eli Manning. Forget not starting. Manning probably shouldn't be on rosters anymore now that Odell Beckham and Brandon Marshall are out for the season. There's simply not enough not upside for now. See where things are at in a few weeks when Sterling Shapard returns from his injury the Giants start using rookie tight end Evan Engram more on the outside.
Bye week: Ezekiel Elliott, LeSean McCoy, Joe Mixon, Thomas Rawls, Eddie Lacy
Jerick McKinnon --
Marlon Mack -- Owners were told to grab Mack late in drafts because the Frank Gore ride will eventually derail and the rookie's all-around game made him the most likely replacement. There hasn't been a takeover, but Mack went for 91 yards and a touchdown on nine carries last week. Don't feel compelled to force Mack into your Week 6 lineup, but he's certainly worth a sign-and-stash.
Adrian Peterson -- The RB-needy Cardinals acquired Peterson from the Saints Tuesday. if available, he's worth a flyer simply based on opportunity. Arizona's backfield remains a mess following David Johnson's injury. The thing is, the offensive line isn't helping the cause which means Peterson won't have tons of help. Still, if he receives 12-18 touches per game, that's hope and that's worth taking a small risk if needed.
Be concerned: Isaiah Crowell has scored a total of 24 fantasy points this season. Seeing as Duke Johnson is making plays and the Browns don't exactly move the ball with ease, Crowell becomes a potential cut option for those aiming for a home run addition.
Others: Wayne Gallman, Elijah McGuire, Samaje Perine
Bye week: A.J. Green, Dez Bryant, Doug Baldwin, Cole Beasley
Will Fuller -- Don't hesitate. Grab the Texans speedster if he's available after scoring four touchdowns over the last two weeks. DeShaun Watson is cruising and going next level with Fuller now in the lineup after an early injury.
Marvin Jones -- This is a strickly Week 6 recommendation. The Lions and Saints should keep the Superdome scoreboard operators busy. New Orleans's secondary is certainly beatable. That's it, that's the call. Jones is fine generally and perhaps better than that in this potential shootout.
Others: Josh Doctson, Cooper Kupp, Nelson Agholor, Mike Wallace, Roger Lewis
Bye week: Jimmy Graham, Jason Witten, Charles Clay
Evan Engram -- This call might not work for most leagues, but the rookie is a must-own following Sunday's injury nightmare. Odell Beckham and Brandon Marshall are done for the season along with Dwayne Harris while Sterling Shepard is out a couple of weeks. The thing is, Eli Manning will still throw 30+ passes and somebody will be targeted on each. The best for lots of work among those not in the backfield is Engram, who has already flashed impressive skills early in his first season.
Austin Sefarian-Jenkins -- He helped needy owners out last week with 6-29-1 and now faces a Patriots defense allowing oodles of production to fantasy tight ends.
Others: Ryan Griffin, Zach Miller, David Njoku
Streamers: Patriots (@ Jets), Redskins (vs. 49ers), Falcons (vs. Dolphins)