Drew Lock and Lockett seemed to build more chemistry as the game went on. DK Metcalf got the faster start, but Lockett won against the 49ers’ defensive backs in the intermediate game. His 89 yards were the most he’s had in a game since Week 10. Lockett remains a low end WR2 option.

Kincaid’s first game with Dawson Knox back off the injured reserve was a bit of a mixed bag. Knox was on the field often, sometimes with Kincaid but sometimes in solo looks, especially when the Bills were looking to run the ball. However, the Bills still used Kincaid in the slot and used a lot of 12 personnel with Kincaid and Knox both on the field, which led to Kincaid actually being second on the team in targets and tied for first on the team in receptions. The Bills passing attack simply was not able to get much going against the Chiefs on Sunday. We don’t want to read into it too much, but Kincaid has the makings of a low-end TE1 the rest of the way.

Edwards-Helaire was the clear lead back for the Chiefs when this game was close, handling all but one running back touch until there was about seven minutes left in the first half. However, the Chiefs were down 14-0 at that point and decided to use Jerick McKinnon as a receiver to get back in the game. What’s worse for CEH is that McKinnon was able to convert a rushing touchdown on a carry from five yards out, which was mean to be CEH’s role. He’s just a touchdown-dependent FLEX option until Isiah Pacheco returns.

Rice led the team in catches as he continues to emerge as the clear top receiver in Kansas City. The Chiefs schemed a great touchdown route for Rice in the third quarter, running Travis Kelce underneath to attract the attention of the safeties and sneaking Rice in behind him. It’s clear that the rookie has become the only reliable pass-catcher aside from Kelce, and his day could have been every bigger as he was also open in the end zone in the second quarter, but he and Mahomes didn’t seem to be on the same page, leading to an incomplete pass. Rice also fumbled late in the third quarter while fighting for extra yardage, but the Chiefs went right back to him on the next offensive play, which shows their confidence in him. He’s a low-end WR2 from here on out.

It was tough sledding for Walker as a runner as the bulk of his 21 rushing yards came on a 12-yard scamper. He found moderate success in the receiving game, but the Niners’ defense was just too stout for Walker to gain any traction. He was out-carried by Zach Charbonnet so it’ll be interesting to see how they divvy up the touches moving forward.

A Raiders defenders rolled up on Mattison’s right ankle and he appeared to be in extreme discomfort on the sideline. Mattison did not return to the game and could miss game action. Ty Chandler would presumably work as the team’s lead back if Mattison misses Week 15 against the Bengals. Chandler would be a top-24 option in such a scenario.

Kittle was mostly involved as blocker, but was able to get a few chunk plays including a 44-yard touchdown in the fourth quarter. His other big chunk play came as he beat the defender running up the sideline and Brock Purdy was able to hit him in stride. Kittle has been more consistent and has performed much like he did in years prior. He’s comfortably back to being a top-five option at the tight end position.

Outside of a lost fumble in the second half, it was business as usual for Aiyuk as he found open spots where Brock Purdy could connect with him easily. His run after the catch ability made it hard for Seahawks’ defenders to contain him all game. He gets a nice matchup in Week 15 as the 49ers go on the road to face the Cardinals.

It wasn’t the most impressive outing for Williams, whose lone score came on a three-yard run following a Justin Herbert interception. Williams had three runs of 10 or more yards on the day and was instrumental on a fourth-quarter drive that ended with a 10-yard touchdown pass to Adam Trautman. Williams’ rushing touchdown was his first ground score of the season, but his volume continues to make him a near must-start as a weekly RB2.

Kelce led the Chiefs in targets and receiving yards, but his game will be remembered for a play that didn’t count. With just over a minute left and the Chiefs down by three, Kelce caught a deep pass from Patrick Mahomes over the middle of the field and, as the Bills defenders were converging on him, lateralled the ball to Kadarius Toney at the Buffalo 15-yard-line. Toney was able to waltz into the end zone for what would have been the game-winning touchdown had he not been lined up offside before the snap. Still, while the game could have been bigger, Kelce remains the focal point of the Chiefs offense and should be in for a big day against the Patriots next week as the Chiefs look to break a run of three loses in their last four games.