The 49ers will be without wide receiver Marquise Goodwin on Sunday when they welcome the Carolina Panthers to Levi's Stadium. 

Goodwin, who has been ruled out because of a personal/family situation, ranks second on the 49ers -- not including newly acquired receiver Emmanuel Sanders -- in receiving yards this season with 181 on 11 receptions. He has scored one touchdown, and also has added 15 rushing yards. 

While San Francisco will be without Goodwin, Sanders will make his 49ers debut. The 10-year pro had 30 receptions for 367 yards and two touchdowns with the Broncos this season before the 49ers acquired him Tuesday

[RELATED: Who else? Sanders is key 49ers player to watch vs. Panthers]

Here is the 49ers' full list of inactives for Week 8.