Welcome to prime time. The undefeated 49ers officially are on the big stage, as their rivalry with the Seahawks has been renewed.
The 49ers face Seattle in their toughest game yet on "Monday Night Football" at Levi's Stadium. It's Nov. 11, but this feels like a playoff game.
There's one problem for the 49ers: They likely will be without star tight end George Kittle, who suffered knee and ankle injuries in last week's win over the Cardinals. QB Jimmy Garoppolo will have to step his game up without one of the best players in the NFL.
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Here's how Las Vegas and the experts around the country see Monday night's battle shaking out.
Line
Caesars: 49ers -6 (-110)
Consensus: 49ers -6 (-110)
Westgate: 49ers -6 (-110)
Wynn: 49ers -6.5 (-110)
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San Francisco 49ers
Predictions
Nick Waggoner, ESPN: 49ers 34, Seahawks 26
Brady Henderson, ESPN: 49ers 34, Seahawks 24
Tadd Haislop, Sporting News: 49ers 26, Seahawks 17
Mike Florio, ProFootballTalk: Seahawks 23, 49ers 13
Tim Kawakami, The Athletic: 49ers 20, Seahawks 14