The 49ers (1-1) take their show on the road to Kansas City on Sunday as they face the Chiefs (2-0) in Week 3 of the 2018 NFL season.
San Francisco will be tasked with trying to slow down Chiefs quarterback Patrick Mahomes, who has thrown 10 touchdown passes and has yet to be intercepted in two games.
Niners running back Matt Breida will look to reclaim his place as the NFL's leading rusher. The second-year pro enters the game with 184 yards, trailing former 49er Carlos Hyde, who has 203 rushing yards following the Browns' win Thursday night.
NFL experts from around the country have made their picks for Sunday's clash, and all of them see the Chiefs dropping the 49ers to 1-2.
Nick Wagoner, ESPN.com: Chiefs 37, 49ers 31
Adam Teicher, ESPN.com: Chiefs 34, 49ers 28
Pete Prisco, CBS Sports: Chiefs 31, 49ers 28
Elliot Harrison, NFL.com: Chiefs 37, 49ers 30
Blair Kerkhoff, Kansas City Star: Chiefs, 30, 49ers 23
Vincent Frank, Forbes.com: Chiefs 41, 49ers 31
This Sunday, be sure to watch 49ers Pregame Live at 9 a.m. on NBC Sports Bay Area and 49ers Postgame Live immediately after the game on NBC Sports Bay Area Plus and live streaming on the NBC Sports app. Greg Papa, Donte Whitner, Jeff Garcia, Matt Maiocco and Laura Britt will have everything you need to know from the 49ers’ game in Kansas City.