For the second straight week, the 49ers (2-7) will play under the prime time lights. Last week, they beat the Raiders on Thursday Night Football. This week, they host the New York Giants (1-7) on Monday Night Football.
After winning his NFL debut, Nick Mullens will once again start at quarterback for the 49ers. Last week, he completed 16 of his 22 passes for 262 yards and three touchdowns. Can he duplicate that performance against the lowly Giants?
The 49ers' defense will get its first look at rookie running back Saquon Barkley, who has 519 rushing yards and five touchdowns on the ground so far this season. Through the air, Barkley has caught 58 passes for 497 yards and four touchdowns.
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Both the 49ers and Giants are in the running for the No. 1 overall pick in the 2019 NFL Draft.
The 49ers enter as 3.5-point favorites over the Giants.
Here's how the experts see things playing out:
Nick Wagoner, ESPN.com: 49ers 24, Giants 20
San Francisco 49ers
Jordan Raanan, ESPN.com: Giants 28, 49ers 24
Pete Prisco, CBS Sports: Giants 28, 49ers 20
Elliot Harrison, NFL.com: 49ers 28, Giants 14
Matt Barrows, The Athletic: 49ers 24, Giants 23
David Lombardi, The Athletic: 49ers 30, Giants 20
Tim Kawakami, The Athletic: 49ers 27, Giants 17
Marcus Thompson II, The Athletic: 49ers 27, Giants 13
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