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Kyler Murray, Richard Sherman
San Francisco 49ers

NFL Week 16 picks, odds: Will 49ers play spoiler vs. Cardinals?

It's hard to believe the 2020 NFL regular season is almost over.

It feels like just yesterday that the 49ers were beginning their "Revenge Tour," the Raiders were filled with hope and promise, Tom Brady was just beginning his transformation into Florida Man, Antonio Brown was still making terrible rap videos and 31 other teams actually thought they had a chance to dethrone the Kansas City Chiefs.

With two weeks left in the season, the playoff picture is taking shape. The 49ers were officially eliminated in Week 15, following their loss to the Dallas Cowboys and the Arizona Cardinals' win over the Philadelphia Eagles. The Raiders' postseason hopes are in the grave and waiting for the dirt to be dumped on them. It will take a heroic effort from Marcus Mariota, and a whole lot of losses elsewhere for Jon Gruden's club to punch a playoff ticket.

Week 16 will see the Seattle Seahawks and Los Angeles Rams face off with first place in the NFC West on the line while the Green Bay Packers battle Derrick Henry and the Tennessee Titans. Meanwhile, Jalen Hurts will look to continue making Doug Pederson look foolish for not yanking Carson Wentz earlier when the Eagles face the Cowboys.

Let's get to the picks.

RECORD: 104-100 SU (133-71-1)
BY  Josh Schrock  - 
Getty Images
It's hard to believe the 2020 NFL regular season is almost over.

It feels like just yesterday that the 49ers were beginning their "Revenge Tour," the Raiders were filled with hope and promise, Tom Brady was just beginning his transformation into Florida Man, Antonio Brown was still making terrible rap videos and 31 other teams actually thought they had a chance to dethrone the Kansas City Chiefs.

With two weeks left in the season, the playoff picture is taking shape. The 49ers were officially eliminated in Week 15, following their loss to the Dallas Cowboys and the Arizona Cardinals' win over the Philadelphia Eagles. The Raiders' postseason hopes are in the grave and waiting for the dirt to be dumped on them. It will take a heroic effort from Marcus Mariota, and a whole lot of losses elsewhere for Jon Gruden's club to punch a playoff ticket.

Week 16 will see the Seattle Seahawks and Los Angeles Rams face off with first place in the NFC West on the line while the Green Bay Packers battle Derrick Henry and the Tennessee Titans. Meanwhile, Jalen Hurts will look to continue making Doug Pederson look foolish for not yanking Carson Wentz earlier when the Eagles face the Cowboys.

Let's get to the picks.

RECORD: 104-100 SU (133-71-1)