James Ward-Prowse ultimately sent the Emirates into a panic.
Arsenal forward Alexandre Lacazette ultimately salvaged a 2-2 draw in the 96th minute, but Southampton's midfielder gave his club a 2-1 lead in the 71st minute Saturday, following up his own rebound after Gunners keeper Bernd Leno saved his penalty.
After Danny Ings caught their defense napping in the eighth minute, Arsenal equalized 10 minutes later through Lacazette. The Gunners seemed well on their way to all through points after playing on the front foot for the vast majority of the second half, but the Saints were able to capitalize on the counter-attack.
Just minutes after Southampton's Cédric Soares failed to pass across the face of goal to wide-open teammate Nathan Redmond, Arsenal left back Kieran Tierney pulled Ings down in the box. A VAR check determined that Ings was not offside before the penalty.
Lacazette made up for it with his second equalizer, but the reaction from Arsenal supporters was hushed at best. When the full-time whistle blew, fans at the Emirates booed the team off the pitch, just as they did at halftime.
[RELATED: Mané gives Liverpool lead after VAR wipes Palace goal]
The Gunners still have not won an English Premier League match since Oct. 6, and they fell to seventh in the table after Saturday's draw. Their North London rivals fired their manager earlier this week, but Tottenham Hotspur now is only one point back of Arsenal after beating West Ham in manager José Mourinho's Spurs debut.
If Arsenal continue to struggle, manager Unai Emery could face a similar fate to former Tottenham counterpart Mauricio Pochettino.
Arsenal supporters breathed a sigh of relief Saturday at the Emirates, thanks to Alexandre Lacazette.
The French forward equalized for the Gunners against Southampton in the 18th minute, scoring just 10 minutes after Danny Ings gave the 18th-placed Saints a 1-0 lead.
Southampton blocked Pierre-Emerick Aubameyang's shot, but Lacazette finished the rebound to score his first goal since Sept. 1.
The sides eventually drew 2-2, meaning Southampton have not won an English Premier League match since beating Sheffield United on Sept. 14th, and haven't won in all competitions since Sept. 24. Arsenal, meanwhile, were winless in the league since Oct. 6 heading into Saturday, and Lacazette's goal surely allowed manager Unai Emery to breathe a sigh of relief, too.
[RELATED: Mourinho era at Tottenham begins with win vs. rival West Ham]
The Athletic's David Ornstein reportedly earlier this month that Arsenal are "100 percent" behind Emery, but North London rivals Tottenham Hotspur making a managerial change of their own conceivably could heat Emery's seat, especially if the Gunners' results don't improve.
Lacazette leveled things Saturday, but drawing against Southampton won't help Emery's case.
A dismal season for Southampton doesn’t get much better as a Saturday matchup with Arsenal looms.
The Saints are just above the cellar of the English Premier League standings, while the Gunners and manager Unai Emery enter this weekend’s showdown ranked No. 6 in England’s top division.
Emery’s name has been on the hot seat as of late, however, as Arsenal is winless through its last four matches, and that seat might just reach a nuclear temperature with a loss to 19th-ranked Southampton.
Without a win since Sept. 14, the Saints appear destined for relegation after narrowly avoiding that fate last season.
Here's how to watch Arsenal versus Southampton live on TV and online:
When: Saturday, Nov. 23, at 10 a.m. ET/7 a.m. PT
TV Channel: NBCSN
Live Stream: NBC Sports