The Boston Celtics appear to be catching a massive break in their Eastern Conference Semifinals matchup with the Milwaukee Bucks.

ESPN's Adrian Wojnarowski reports Bucks All-Star Khris Middleton could miss the entire potential second-round series as he continues to recover from a sprained MCL.

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UPDATE (Thursday, April 28): Middleton has a Grade 2 sprain in his left ACL and is expected to miss the entire Celtics-Bucks series, The Athletic's Shams Charania reported Thursday morning.

Middleton suffered the injury on April 20 and although he initially was supposed to be reevaluated in 1-2 weeks, Wojnarowski said Wednesday the team anticipates him missing even more time.

“There’s not a sense that he’s going to get reevaluated at two weeks and then all of a sudden be back at practice and be ready to play,” Wojnarowski said on NBA Today.

Middleton being sidelined for the series significantly hurts the defending champions' chances of advancing to the Eastern Conference Finals. The 30-year-old has a history of success vs. the Celtics and would have presented another tough challenge for Boston's defense alongside two-time MVP Giannis Antetokounmpo.

In his last nine games vs. the C's from 2019-22, Middleton has averaged 20.3 points, 7.3 rebounds, and 5.6 assists.

Celtics-Bucks Game 1 is scheduled for Sunday at 1 p.m. ET at TD Garden, with coverage on NBC Sports Boston beginning at 12 p.m. ET.