Watch DeAndre Hopkins make insane catch as Cardinals stun Bills on Hail Mary TD


DeAndre Hopkins' absolutely incredible catch on a game-winning Hail Mary touchdown pass for the Arizona Cardinals on Sunday afternoon is going to be a highlight reel staple for many years to come.

The Cardinals were trailing the Buffalo Bills 30-26 with 11 seconds remaining in the fourth quarter when Arizona quarterback Kyler Murray hurled a deep pass for the end zone.

Perry's Mailbag: What's the realistic QB plan in 2021?

Hopkins was covered by three (!) Bills players and still managed to catch the ball for the winning score.

Check out the all-time great reception in the video below: 

Here's another look at Hopkins' unreal grab:

It was a heartbreaking defeat for the Bills, who had taken the lead on the previous drive when quarterback Josh Allen made arguably the best throw of his career.

The loss also impacts the AFC East title race in a potentially huge way.

The Bills remain in first place, but just barely, with a 7-3 record. The Miami Dolphins are right behind the Bills with a 6-3 record after beating the Los Angeles Chargers on Sunday afternoon. The Bills and Dolphins will close out the regular season with a Week 17 matchup in Buffalo.

Brady, Brown thrive in Bucs' dominant win over Panthers

The New England Patriots, who host the Baltimore Ravens on "Sunday Night Football", are 3-5 in third place and unlikely to win the AFC East for the 12th consecutive season. The New York Jets sit at the bottom of the division at 0-9. 

The AFC East title race has been a snoozefest for most of the 21st century as the Patriots have won it 17 times over that span. This season is shaping up to be much different, though, and that's very exciting for fans in Buffalo and Miami.