Patriots vs. Bills betting odds: Week 13 moneyline, spread


The train in Foxboro keeps on rolling.

The New England Patriots made it six wins a row, improving their record to 8-4 with a 36-13 win over the Tennessee Titans in Week 12. 

Mac Jones threw for 310 yards and two touchdowns, both to Kendrick Bourne, who finished the day with five catches for 61 yards. Jakobi Meyers paced all receivers with five catches for 98 yards.

While the defense allowed 270 rushing yards to a Titans rushing attack that was without Derrick Henry and Jeremy McNichols, they also picked off Ryan Tannehill in the endzone and forced three fumbles. Tannehill was limited to a season-low 93 passing yards. 

The Pats will put their winning streak on the line yet again, this time in upstate New York under the bright lights of Monday Night Football against an AFC East foe, the Buffalo Bills.

The Bills, right behind the Patriots at 7-4, took care of business on Thanksgiving against the New Orleans Saints, crushing them to the tune of 31-6. Josh Allen threw for 260 yards and four touchdowns in the win. 


The matchup on Monday night has major division title implications. The Bills can leapfrog the Pats for the division lead with a win, while the Patriots can separate themselves for first place if they come out on top. 

Here is the betting info for Monday’s game:

Patriots vs. Bills Moneyline, Spread and Total

Line: Bills -2.5

Over/under: 41.5

Patriots team total O/U: 20.5

Bills team total O/U: 24.5

Moneyline: Patriots +125 | Bills -145

You had to go all the way to the pre-Tom Brady era in New England to find a season where the Patriots didn’t get at least one win against the Bills. But that changed last year. 

The Bills won both matchups against the Patriots for the first time since 1999, with a close 24-21 victory in Week 8 before blowing out the Pats 31-9 in Week 16. However, it’s safe to say this New England team is not the same as last. 

Here are the full odds for the Patriots-Bills game.

For info on how to watch the game, click here.

All odds provided by our partner, PointsBet.

Patriots Props to Watch for Week 13

Mac Jones passing yards O/U: 205.5


Damien Harris rushing yards O/U: 50.5

Jakobi Meyers receiving yards O/U: 40.5

Kendrick Bourne receiving yards O/U: 35.5

Fresh off his best passing game of the season (310 yards), Mac Jones is projected to come back down to earth against a strong Bills defense. He’s surpassed 210 yards in eight of 12 games this season, so PointsBet could be selling Jones short. On the other end, Damien Harris' role has decreased in recent weeks with Rhamondre Stevenson’s emergence. He’s failed to top 50 rushing yards in two of his last three games.

Patriots ATS Record and Game Results

The Patriots easily covered as seven-point favorites against the Titans, improving to 8-4 against the spread for the season.

Here are some takeaways from the Patriots’ Week 11 performance:

Sign up for NBC Sports Edge+ for up-to-the-minute positional rankings, betting help and game predictions.

Patriots Future Bets Before Week 13

The Patriots’ odds of winning the division keep improving in the eyes of oddsmakers with their winning streak extended to six. 

Patriots to make the playoffs -1500

Patriots to win the AFC East +105 (second-best in division)

Patriots to win the Super Bowl +1100

Here are some of the odds for various Patriots players to win season-long awards:

Mac Jones to win Offensive Rookie of the Year -400 (first in the NFL)

Mac Jones to win Most Valuable Player +10000

Christian Barmore to win Defensive Rookie of the Year +3300 (fifth in the NFL)

Matthew Judon to win Defensive Player of the Year +800 (third in the NFL)

Bill Belichick to win Coach of the Year +300 (tied for first in the NFL)


The full docket of NFL futures can be found at PointsBet here.

Editor's note: All odds are provided by our partner, PointsBet. PointsBet is our Official Sports Betting Partner and we may receive compensation if you place a bet on PointsBet for the first time after clicking our links