Mac Jones will have a (nearly) full complement of weapons at his disposal in his NFL debut.
Cornerback Jalen Mills (questionable with an ankle injury) also is set to make his Patriots debut Sunday after going through pregame tests on his ankle.
That's good news for New England, which is already down top cornerback Stephon Gilmore and will rely on Mills to complement J.C. Jackson and Jonathan Jones on the outside.
Meanwhile, Jones will have a deep threat in the passing game with Agholor, who joins wide receivers Jakobi Meyers and Kendrick Bourne and tight ends Jonnu Smith and Hunter Henry among the rookie quarterback's weapons against Miami.
The Patriots' surprise inactive is running back J.J. Taylor, who enjoyed a strong preseason. But rookie rusher Rhamondre Stevenson had an even better summer and gives New England plenty of depth behind Damien Harris and James White.
Veteran Nick Folk also will handle kicking duties after being called up from the practice squad Saturday, as rookie kicker Quinn Nordin is inactive.
Here are the full inactive lists for the Patriots and Dolphins.
New England Patriots inactives
LB Ronnie Perkins
RB J.J. Taylor
TE Devin Asiasi
OT Yodny Cajuste
CB Shaun Wade
K Quinn Nordin
Miami Dolphins inactives
CB Trill Williams
CB Noah Igbinoghene
DB Elijah Campbell
OT Greg Little
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