PITTSBURGH (AP) -- Gift Ngoepe might not have had the weight of the world on his shoulders but he felt like a continent was counting on him.
Ngoepe, the first African to reach the major leagues, singled in his first plate appearance and Josh Harrison led off the bottom of the first with a home run Wednesday night to lead the Pittsburgh Pirates to a 6-5 victory over the Chicago Cubs.
Ngoepe was recalled from Triple-A Indianapolis and entered the game in fourth inning as part of a double switch and finished 1 for 2 with a walk. The 27-year-old South African, who signed with the Pirates in 2008 as an amateur free agent, led off the fourth with a hit off winless Cubs ace Jon Lester.
"To accomplish this only for me but for my country and my continent is something so special," Ngoepe said. "There are 1.62 billion people on our continent. To be the first person out of 1.62 billion to do this is amazing."
It was so special that Ngoepe nearly broke into tears when he trotted from the dugout to take his positon at second base.
"I told myself not to cry because I'm in the big leagues and I'm a big guy now," Ngoepe said with a smile. "(Catcher Francisco) Cervelli hugged me and I could feel my heart beat through my chest."
A year after winning 19 games in helping the Cubs win their first World Series title since 1908, Lester (0-1) is still looking for his first victory after five starts. The left-hander was tagged for six runs - five earned - and 10 hits in 5 2/3 innings.
"It's probably the best I threw the ball all year," Lester said. "That's baseball."
Wade LeBlanc (1-0), who pitched 1 1/3 scoreless innings in relief of rookie Tyler Glasnow, got the win.
The fifth leadoff home run of Harrison's career keyed a two-run first that included an RBI double by Cervelli. Andrew McCutchen and Phil Gosselin hit run-scoring doubles in a three-run third that pushed the Pirates' lead to 5-1.
After the Cubs got within two runs, Josh Bell gave the Pirates a 6-3 lead with a solo home run in the sixth inning off Lester. The rookie first baseman has reached base in 11 straight games.
Anthony Rizzo's two-run homer deep into the right-field stands in the eighth inning off Daniel Hudson drew the Cubs within 6-5. Tony Watson then got the last four outs for his seventh save in as many chances.
Glasnow remained winless in nine career starts, allowing three runs in 3 1/3 innings and requiring 89 pitches to get 10 outs.
Rizzo had four RBIs and Kris Bryant had three hits as the Cubs lost for just second time in eight games while stranding 13 runners. The Pirates won for the third time in nine games.