At one point in Friday's game, the Cubs led by three runs.
It took half an inning for the Marlins to erase that deficit and take a commanding lead. The Cubs battled late but came up short, falling 14-10 in the series opener — their ninth straight loss.
Here are 10 observations from the game.
1. Adbert Alzolay exited after 1 1/3 innings with left hamstring tightness. The right-hander spent a chunk of the top of the inning running the bases, hitting a double and moving to third on a single.
Alzolay was getting treatment postgame and will be evaluated Saturday.
2. Alzolay gave up a season-high five earned runs before exiting, the big blow being a grand slam on a hanging slider. Miami loaded the bases on two singles and a walk.
"That guy is so competitive," catcher Robinson Chirinos said of Alzolay. "He wants to give this team a chance to win a game. You could see the pain through his eyes and how he felt when he came out of the game."
3. The Marlins scored seven more runs after the slam for 11 total in the inning, sending 15 batters to the plate. Dan Winkler, thrust into action in place of Alzolay, was charged with six runs on four hits without getting an out. Miami pitcher Jesús Luzardo batted twice and was responsible for two of the inning’s outs.
4. How long was the second inning? Luzardo went 55 minutes between his last pitch of the second and first pitch of the third.
5. Opponents have scored early and often against the Cubs this week. Friday was the third straight game they allowed five or more runs in the first two innings. It’s the first time any MLB team has done that since the Orioles in 1993, according to ESPN Stats and Info.
6. For as much as the Cubs trailed Friday, they actually tallied a season-high in hits, out-hitting the Marlins 18-12. They scored four times in the eighth inning on two-run blasts by Frank Schwindel and Ian Happ.
Schwindel, whom Ross pregame called "a real bright spot" since joining the club last month, went 3-for-5, adding a double.
7. Reliever Codi Heuer delivered his fifth scoreless appearance in six tries since coming over from the White Sox in the Craig Kimbrel trade. Heuer, who allowed two runs in his last outing, pitched two scoreless innings Friday.
8. David Bote helped give the Cubs that early lead with a two-run home run in the first inning. Bote, who’s struggled since coming off the injured list last month (.190/.262/.310 in 18 games entering Friday) finished the night 2-for-4.
9. Chirinos came 90 feet shy of hitting for the cycle. He struck a line drive into the right field corner in the eighth inning that had potential to be a cycle-clinching triple. He held at second base for his second double of the night, finishing 4-for-6.
Chirinos said he was aware he needed a triple for the cycle but didn't think it made sense to try for three bases.
"[Marlins right fielder Bryan De La Cruz] did everything right in the outfield," Chirinos said.
10. Rowan Wick's second appearance since last September was briefly delayed by an issue with the color of his glove. Wick wasn't allowed to use the bright gray mitt and changed to a blue one.
Wick, who returned this week from a serious oblique injury sustained last season, pitched a 1-2-3 seventh with one strikeout.
On deck: First pitch Saturday is 5:10 p.m. CT. Zach Davies (6-9, 5.26 ERA) is the Cubs’ probable starter. Miami’s is TBD.