Another week. Another rash of injuries in the NFL.
Odell Beckham Jr. was one of three New York Giants wide receivers to go down with season-ending injuries. Bilal Powell, DeVante Parker and Travis Kelce all exited their team's victories after getting struck by the injury bug.
While the majority of these injury cases won't really do much in terms of elevating another player from obscurity to fantasy relevance, we've done our best to gather a list of reinforcements who could be worth a roster spot on a thin waiver wire week.
Here's a list of 10 players who should provide some help in Week 6 and beyond.
1. Adrian Peterson, RB, ARI
Just when you thought you could forget about the artist formerly known as AP, the Arizona Cardinals go out and make him fantasy relevant once again. The Cardinals pulled off a rare in season trade by dealing a 2018 conditional draft selection to the New Orleans Saints for Peterson on Tuesday morning. While Peterson looked pedestrian at best (81 yards on 27 carries) during his four games with the Saints in 2017, the trade gives him an opportunity to join a backfield in which he'll likely be in line for early-down work and an offense which better suits his running style. In a week where there aren't many upgrades on the waiver wire, Peterson has the chance to provide flex value in Arizona.
2. Jerick McKinnon, RB, MIN
If you watched Monday's Bears-Vikings game, you'd know that McKinnon is hands down the best running back on the Vkings roster. Murray plodded his way to a meager 31 yards on 12 carries while McKinnon took control of the backfield with 16 carries for 95 yards and a touchdown, while also adding six receptions for 51 yards. McKinnon has teased us before, flashing high upside and off the charts athleticism early on in Minnesota, so it's easy to be pessimistic, but he's currently the only quality back in Minnesota and he'll certainly get the touches moving forward.
3. Aaron Jones, RB, GB
If you missed out on Jones last week, shame on you. He's currently owned in 66 percent of leagues, meaning there's still a chance he could be available for you. If so, he should be your No. 1 priority. Jones looked explosive in his first career start against the Cowboys, rushing for 125 yards and a touchdown with an eye-popping 6.6 yards per carry. Even if starting running back Ty Montgomery returns this week, there's a good chance the Packers ride the hot hand until Montgomery is 100 percent.
4. Elijah McGuire, RB, NYJ
As the first-place Jets (try saying that with a straight face) get set for a showdown with the New England Patriots, they'll likely be without Bilal Powell (calf) and Matt Forte (knee), meaning the rookie McGuire will be in line for a heavy workload against a Patriots defense that's allowing the second-most fantasy points to opposing running backs. McGuire doesn't possess the highest ROS upside, and he'll likely be relegated to third-string duties once the Jets are fully healthy at running back, but he's a player that should be targeted for the FLEX position in a juicy Week 6 matchup.
5. Marlon Mack, RB, IND
The rookie out of South Florida had the best game of his young NFL career on Sunday, rushing for 91 yards on nine carries and flashed his explosiveness with a 35-yard touchdown run. Mack won't be stealing Frank Gore's starting job anytime soon, but his big-play ability and change-of-pace style could force the hand of head coach Chuck Pagano. As of now, Mack is stash and watch candidate who could provide major value later in the season.
6. Matt Breida, RB, SF
Following the 49ers loss to the Colts, head coach Kyle Shanahan uttered the words no fantasy owner likes to hear, "the team will use a hot hand approach" at running back. This news, coupled with Carlos Hyde's lingering hip injury, means Breida needs to be scooped up in all formats. Breida has seen an uptick in touches in every game this season, and had a career-high 10 carries for 49 yards in Week 5. Look to see those touches continue to climb moving forward.
7. Ricardo Louis, WR, CLE
The wide receiver position has been like a game of musical chairs for the Browns this season. One week it was Corey Coleman, then it was Rashard Higgins, after that it was Kenny Britt, and as of late it's been Louis. A fourth-round draft choice in 2016, Louis has shown promise in Year 2 as he's seen 17 targets the last two weeks and hauled in 10 receptions for 135 yards. For a team that's going to be playing from behind in a majority of games this season, Louis is a must-add as the current de facto No. 1 in Cleveland.
8. Juju Smith-Schuster, WR, PIT
The Steelers have been searching for a viable No. 2 option in the passing game behind All Pro wide receiver Antonio Brown, and while we all thought this would be the year that Martavis Bryant breaks out, his struggles have forced the Steelers to get Smith-Schuster more involved in the offense. The rookie wideout has seen more snaps than Bryant over the last three games and has seven receptions on targets for 105 yards and a touchdown in his last two contests. Smith-Schuster may not be a WR2/FLEX option just yet, but he's worth stashing.
9. Austin Seferian-Jenkins, TE, NYJ
We've been waiting for ASJ to become fantasy relevant for years now, and it appears his time has finally come. Seferian-Jenkins caught his first touchdown in a Jets uniform in Sunday's victory over the Browns. Since returning from suspension, he's hauled in 15 receptions for 106 yards and a score. On a team that's thin at weapons in the passing game, ASJ is a must-own in all league formats.
10. Jacoby Brissett, QB, IND
With injuries piling up (Marcus Mariota and Derek Carr) and players on bye weeks (Dak Prescott, Russell Wilson and Tyrod Taylor), now may be the time you need to hit the wire in search for a streaming option at the quarterback position. Despite not throwing a touchdown pass, Brissett had his best day as a passer, tossing for 314 yards in a win over the 49ers. Brissett's steady play should continue against one of the league's most charitable defenses (TEN) for opposing signal callers. If you're looking for a one week option, Brissett should be your guy.