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49ers rule Deebo Samuel out

Mike Florio and Chris Simms discuss how Christian McCaffrey will be a real factor in Week 8 and why San Francisco has the edge over Los Angeles.

49ers General Manager John Lynch said on Friday morning that wide receiver Deebo Samuel is the kind of player that the team gives as much time as possible to show that he’s healthy enough to play, but they obviously don’t think there’s any benefit into taking a decision about this Sunday’s game against the Rams into the weekend.

The 49ers ruled Samuel out after he missed his third straight practice with a hamstring injury. It will be the first game that Samuel has missed this season and his absence could set the stage for running back Christian McCaffrey to play a more sizable role in his second game with the team.

Linebacker Dre Greenlaw (calf), fullback Kyle Juszczyk (finger), and defensive tackle Arik Armstead (foot, ankle) are also going to be out for the 49ers this weekend.

Wide receiver Jauan Jennings (hamstring) and cornerback Jason Verrett (knee) are listed as questionable.