Tramaine Isabell scored 22 points to lead five Dragons in double figures, made 11 of 14 free throws and handed out five assists as Drexel pulled away early from Division III member Arcadia University to win 95-81 on Monday night.
Troy Harper added 17 points and grabbed eight rebounds, Sammy Mojica added 13 points with five assists, Kurk Lee had 11 points, and Austin Williams, 10 for Drexel (2-0).
Arcadia's Josh Scott tied it at 2 with a layup, but Drexel quickly pulled ahead on a 10-3 run in which Jarvis Doles made a 3 and led 51-42 at halftime behind Harper's 15 points and on 55.2 percent shooting from the floor.
The Dragons shot 58.8 percent early in the second half and led 81-60 after Isabell hit a pair of free throws, and cruised.
Da'Kquan Davis scored 18 points for the Knights, who play in the Mid Atlantic Conference. Josh Scott and Brandon Thompson scored 14 apiece, with Thompson shooting 4 of 8 from 3-point range, and Phil Pierfy added 13 points.
It was the first meeting of the teams.
Jordan Roland had 26 points as Northeastern easily defeated Drexel 90-66 on Saturday. Vasa Pusica added 21 points for the Huskies. Pusica also had nine rebounds for the Huskies.
Anthony Green had 14 points and nine rebounds for Northeastern (20-10, 14-4 Colonial Athletic Conference), which earned its fourth straight victory. Bolden Brace added nine rebounds.
Northeastern totaled 53 second-half points, a season best for the team.
Camren Wynter had 19 points and eight assists for the Dragons (13-18, 7-11). Alihan Demir added 14 points and nine rebounds. Trevor John had 11 points.
The Huskies improve to 2-0 against the Dragons this season. Northeastern defeated Drexel 93-83 on Dec. 28. The Huskies and the Dragons next take the floor in the Colonial Athletic Conference Tournament.
Justin Wright-Foreman had 32 points as Hofstra narrowly defeated Drexel 80-77 to earn at least a share of the Colonial Athletic Association title on Thursday night.
Eli Pemberton had 15 points and six rebounds for Hofstra (24-6, 14-3), which has a one-game lead over Northeastern with one game left to play. Desure Buie added 15 points. Jalen Ray had 10 points for the visiting team.
Alihan Demir had 24 points for the Dragons (13-17, 7-10). Trevor John added 20 points and six rebounds. James Butler had 18 points.
The Pride improve to 2-0 against the Dragons this season. Hofstra defeated Drexel 89-75 on Dec. 30. Hofstra finishes out the regular season against Delaware on the road on Saturday. Drexel finishes out the regular season against Northeastern at home on Saturday.