The Phillies got an important player back from the injured list on Wednesday, but for the second day in a row had to place an important player on the IL.
Andrew McCutchen, who had been out with knee inflammation, was activated and in the starting lineup, playing left field and batting cleanup against the Los Angeles Dodgers.
Reliever Connor Brogdon was also activated from the IL.
Meanwhile, Jose Alvarado, one of the team's key late-game relievers, was placed on the IL with an impingement in his left shoulder. He followed first baseman Rhys Hoskins, who went on the IL with a groin strain Tuesday.
Alvarado last pitched Saturday when he racked up his third straight scoreless appearance. He has pitched in 45 games this season.
The Phils also sent lefty Damon Jones back to Triple A. That move, along with Alvarado's assignment to the IL, left the team with just one left-hander, Matt Moore, in the bullpen, and his availability is probably limited because he is penciled in to start Saturday's game against Cincinnati.
Alvarado said he recently felt fatigue and weakness in his left shoulder. An MRI on Wednesday revealed the impingement.
"It's like death," Alvarado said of his unexpected setback. "You never know when it's going to happen. One day you are here, one day you are not. I was feeling fine one day, then I started feeling weak. But I'm confident I will come back strong.
"Maybe I'm tired and I need a little rest."
On the other side of the field, the Dodgers placed Mookie Betts on the IL with a hip injury before the game.
The Phillies' lineup had a different wrinkle as Alec Bohm was set to make his first start of the season at first base. He made three starts at the position last season.
Here is the Phillies' lineup against Dodgers' lefty David Price:
1. Jean Segura 2B
2. J.T. Realmuto C
3. Bryce Harper RF
4. Andrew McCutchen LF
5. Alec Bohm 1B
6. Didi Gregorius SS
7. Ronald Torreyes 3B
8. Odubel Herrera CF
9. Kyle Gibson P