Anthony Russo threw two touchdown passes and Temple took advantage of four turnovers by Memphis to upset No. 23 Memphis 30-28 on Saturday.
Brady White passed for 355 yards and two scores for Memphis (5-1, 2-1 American), which fell behind 16-0 as the Owls turned the Tigers' mistakes into points.
The win was secured when an apparent diving catch for Tigers tight end Joey Magnifico to convert a fourth-and-11 was overturned by instant replay with 1:50 to play in the fourth. It would have placed Memphis inside the Temple 30, but instead the Owls (5-1, 2-0) were able to burn the clock.
Jager Gardner ran for a score and Isaiah Wright and Brandon Mack caught touchdown passes for Temple. Russo's 12-yard touchdown to Mack made it 30-21 with 12:48 left in the fourth.
Russo threw for 224 yards on 20-for-33 passing.
Kenneth Gainwell had eight catches for 98 yards and rushed 19 times for 107 yards and a touchdown for Memphis.
Memphis: The Tigers were able to move the football effectively against a Temple defense that had averaged 292.4 yards in yield through the first five games of the season. Memphis posted 502 yards of total offense.
Temple: The Owls could have buried Memphis early, but the first three Memphis turnovers were turned into Will Mobley's three field goals.
Memphis: Entering Saturday at the No. 23 spot, the Tigers are likely to fall out of the poll after appearing in it for the first time this week.
Temple: The Owls have wins over two teams that were ranked in the Top 25 at the time of their contest, though Maryland has crashed since then. Temple might not break into the rankings this week but with No. 21 SMU and UCF up next, it has plenty of chances to impress.
Memphis: The Tigers return home to face Tulane in a Saturday night.
Temple: The Owls visit SMU.