Denver Broncos quarterback Peyton Manning (18) signals a touchdown after throwing his 508th career touchdown pass during the first half.

A banner is waved after Denver Broncos quarterback Peyton Manning threw his 509th career touchdown pass during the first half.

Denver Broncos quarterback Peyton Manning (18) celebrates his 509th career touchdown pass with teammates during the first half.

San Francisco 49ers quarterback Colin Kaepernick (7) throws against the Denver Broncos during the first half.

Denver Broncos wide receiver Demaryius Thomas, right, scores a touchdown as San Francisco 49ers strong safety Antoine Bethea (41) and Perrish Cox defend during the first half.

Denver Broncos outside linebacker Von Miller, rear, tackles San Francisco 49ers quarterback Colin Kaepernick (7) during the second half.

San Francisco 49ers wide receiver Anquan Boldin (81) bobbles a pass before catching it as Denver Broncos cornerback Bradley Roby (29) defends during the first half

Denver Broncos running back Ronnie Hillman (23) is hit by San Francisco 49ers cornerback Tramaine Brock (26).

San Francisco 49ers wide receiver Stevie Johnson (13) scores a touchdown against the Denver Broncos. 

Denver Broncos quarterback Peyton Manning (18) throws his 509th career touchdown pass during the first half.