Orioles third baseman Manny Machado went on a profanity-laden tirade about the Red Sox on Tuesday night.

Machado was unhappy with the Red Sox after pitcher Chris Sale threw a retaliatory pitch at him during the Orioles’ 5-2 loss at Fenway Park in Boston.

"I've lost my respect for that organization, for that coaching staff, for everyone over there," Machado told reporters.

During the first inning, Sale’s first pitch to Machado was thrown behind his legs, which resulted in a bench warning for both teams.

In Monday’s contest, Orioles pitcher Dylan Bundy hit Red Sox outfielder Mookie Betts in retaliation for Red Sox reliever Matt Barnes throwing a pitch behind Machado’s head during an April 23 meeting.

Two days before that, Machado made a hard slide that injured Red Sox second baseman Dustin Pedroia.

Machado hit a solo home run off Sale during the seventh inning Tuesday to cut the Red Sox's lead to 3-2.

Sale’s pitch at Machado came one at-bat after he stepped off the mound to allow Red Sox fans to give Orioles center fielder Adam Jones a prolonged ovation following racial taunts he received during Monday night’s game.