After taking care of business against Saint Louis and Liberty in the first two rounds, Virginia Tech has reached its first Sweet Sixteen since 1967.

However, the fourth-seeded Hokies now face a daunting task against No. 1 overall seed and ACC rival Duke. 

Virginia Tech did beat the Blue Devils in their only previous meeting this season, winning a 77-72 contest at Cassell Coliseum on Feb. 26. But Duke did not have Zion Williamson that night, and the superstar forward will be in the starting five when the two teams face off in the East Regional Semifinal on Friday, March 29. 

That said, Duke is coming off a major scare from UCF in the second round, the Blue Devils barely scraping out a 77-76 victory over the Knights. Will playing a de facto home game at Capital One Arena give the Hokies some hope?

Here is the NCAA Tournament information:

Virginia Tech vs. Duke How to Watch

What: 2019 NCAA Tournament East Regional Semifinal (Sweet Sixteen)

Who: No. 4 Virginia Tech (26-8, 12-6 ACC) vs. No. 1 Duke (31-5, 14-4 ACC)

When: 9:39 p.m. ET on Friday, March 29

Where: Capital One Arena, Washington, D.C. 

TV Channel: CBS

Online Stream: March Madness Live on NCAA.com

TV Announcers: Jim Nantz / Bill Raftery / Grant Hill // Tracy Wolfson 

Twitter: @HokiesMBB@DukeMBB

 

Virginia Tech vs. Duke Bracket Analysis

How They Got Here: Virginia Tech (at-large), Duke (auto-bid, ACC champions)

Previous Meeting: 77-71 Saint Louis win on Nov. 16, 2017 (Virginia Tech leads all-time series 7-1)

Next Round: Winner of No. 2 Michigan State vs. No. 3 LSU

East Region Bracket:

No. 1 Duke vs. No. 4 Virginia Tech

No. 2 Michigan State vs. No. 3 LSU

Virginia Tech vs. Duke Betting Spread, Lines & Odds

Favorites: Duke -7
Over/Under: 144
Money Line: Virginia Tech +275, Duke -330
Against The Spread: Virginia Tech (18-15-1), Duke (18-18)

Betting lines found on BetOnline.ag

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