The NFL’s decision to get rid of the “Probable” injury designation has resulted in an overwhelming majority of players being labeled “Questionable” ahead of Sunday. Luckily, we can mostly sift through the noise and determine which questionable players have a good or bad chance of playing by tracking daily practice participation and news.
You can view every injured player’s daily practice participation as well as their estimated and official game status in the table below, but first let’s break down some of the week’s most-important news to monitor.
Fantasy preview: KC-CHI
We could be in store for a fun game when the Chiefs travel to Chicago to battle the Bears in Week 16.
- Panthers TE Greg Olsen (concussion) has cleared the protocol and will be healthy enough to suit up this Sunday. Ian Thomas will be a non-viable fantasy option if Olsen is ultimately active. Still, the Panthers declined to name a starting QB on Monday, so treat whoever winds up starting at TE with caution if rookie QB Will Grier draws the start.
- Bears WR Taylor Gabriel (concussion) has missed back-to-back games, allowing now-No. 2 WR Anthony Miller to flourish. The matchup this week against the Chiefs isn’t ideal for the passing game, but both Allen Robinson and Miller can be fired up as solid fantasy options if Gabriel remains sidelined.
- Bengals WR A.J. Green (ankle) has reportedly not given up on the season just yet. His Week 16 smash spot against the Dolphins would be awfully appealing if we get any sort of update regarding whether or not he’ll play a full-time role if active. Both Tyler Boyd and John Ross would be in play as upside fantasy options if AJG is again inactive.
- Broncos TE Noah Fant (shoulder) missed about a quarter of the team’s Week 15 loss to the Chiefs. He’s expected to suit up Sunday against the Lions, but backup TE Jeff Heuerman will continue to be annoyingly involved. It’s probably not wise to expect too much consistency from any pass-game options in this offense other than Courtland Sutton.
- Lions QB Matthew Stafford (hip, back) remains week to week and isn’t expected to take another snap this season. Injuries to RBs Bo Scarbrough (ribs) and J.D. McKissic (stinger) could again lead to a starting role for Wes Hills, although Ty Johnson along with any other random RB that the Lions decide to promote to the active roster this week could also be plenty involved.
- Jaguars WR D.J. Chark (foot) seems unlikely to be rushed back to action after sporting a walking boot for most of last week. The offense will continue to roll with Chris Conley, Dede Westbrook and Keelan Cole if Chark remains sidelined against the Falcons in Week 16.
- Chiefs RB Damien Williams (ribs, illness) isn’t guaranteed to walk back into a featured role once active, as the offense has consistently utilized each of LeSean McCoy, Spencer Ware and Darwin Thompson during his absence. None should be treated as anything more than boom-or-bust RB4s regardless of who suits up.
- Rams TE Gerald Everett (knee) has missed three consecutive games and doesn’t appear particularly close to a return after failing to practice again last week. Continue to fire up Tyler Higbee as a weekly TE1 in his absence. The fourth-year TE has posted 7-107-1, 7-116-0 and 12-111-0 performances over the past three weeks.
- Vikings RBs Dalvin Cook (shoulder) and Alexander Mattison (ankle) are all kinds of banged up. Look for SPARQ-plug/preseason-superstar Mike Boone to work as the offense’s lead back if both are ultimately sidelined, although Ameer Abdullah would also likely see plenty of work on pass downs. ESPN’s Adam Schefter said it would be “surprising” if Cook plays in either Week 16 or 17.
- Giants TE Evan Engram (foot) appeared close to a return in Week 15, while Rhett Ellison (concussion) has now missed four consecutive games. Kaden Smith will continue to play a near every-snap role if both Engram and Ellison remain sidelined. Either Smith or Engram would be worthy of borderline TE1 consideration with a full-time role, but keep in mind this is a low-ceiling passing attack that is fairly crowded with the team’s top-three WRs and Saquon Barkley also more than worthy of targets.
- Eagles RB Jordan Howard (shoulder) and WR Nelson Agholor (knee) have been deemed questionable for the last few weeks only to eventually get ruled out on Saturday. Perhaps Week 16’s season-defining matchup against the Cowboys will get both back onto the field. Still, limited snaps and opportunities are likely for both considering the success of Miles Sanders, Boston Scott and Greg Ward in Week 15.
- Raiders WR Hunter Renfrow (ribs) is expected to suit up for the team’s Week 16 matchup against the Chargers. Renfrow has missed the last three games with a broken rib and punctured lung. His return will likely lead to three-WR sets featuring himself, Tyrell Williams and Zay Jones. Still, Darren Waller is the only consistent fantasy option in this offense at the moment.
- Steelers TE Vance McDonald (concussion) could be viewed as an upside TE2 in Week 16 against the Jets if he’s active AND SS Jamal Adams (ankle) remains sidelined. JuJu Smith-Schuster (knee) faces volume concerns in this run-first offense if healthy enough to return, but could be treated as a boom-or-bust WR3 against this atrocious group of corners.
- Buccaneers WRs Mike Evans (hamstring), Chris Godwin (hamstring) and Scotty Miller (hamstring) are each expected to sit out with their respective soft-tissue injuries. This means Breshad Perriman, Justin Watson and AAF-champion Ishmael Hyman should mostly work out of three-WR sets. Note that OJ Howard (8 targets in Week 15) and Cameron Brate (7) also figure to be plenty involved as receivers.
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The below injury dashboard denotes every player listed on all 32 team’s injury reports as well as those that are currently suspended or on the IR/PUP. “DNP” stands for “Did Not Practice”, “LP” stands for “Limited Practice” and “FP” stands for “Full Practice”.
Be sure to follow our industry-leading player news for up-to-the-minute analysis on injuries and transactions around the league.
Editor’s Note: Drafting is only half the battle. Dominate all season long with our Season Pass! Use our NEW Start/Sit Tool, Trade Analyzer, Consensus Rankings, Projections and more on your way to a championship! Click here for more!
| Week 16 | Tm | Pos | Injury | Tm Status | RW Status | M | Tu | W | Th | F |
| Haason Reddick | ARI | LB | Groin | In | In | - | - | FP | FP | FP |
| Christian Kirk | ARI | WR | Ankle | Ques | Ques | - | - | DNP | LP | LP |
| Jordan Hicks | ARI | LB | Calf | In | In | - | - | DNP | LP | FP |
| Justin Pugh | ARI | OL | Back | Ques | Ques | - | - | DNP | DNP | LP |
| Caraun Reid | ARI | DT | Knee | Ques | Ques | - | - | LP | LP | FP |
| Joe Walker | ARI | LB | Ribs | In | In | - | - | LP | FP | FP |
| Tanner Vallejo | ARI | LB | Ribs | IR | IR | - | - | - | - | - |
| Rodney Gunter | ARI | DL | Toe | IR | IR | - | - | - | - | - |
| Jonathan Bullard | ARI | DL | Hamstring | IR | IR | - | - | - | - | - |
| Zach Allen | ARI | DE | Neck | IR | IR | - | - | - | - | - |
| Brooks Reed | ARI | LB | Hamstring | IR | IR | - | - | - | - | - |
| D.J. Foster | ARI | RB | Hamstring | IR | IR | - | - | - | - | - |
| Marcus Gilbert | ARI | OL | Knee | IR | IR | - | - | - | - | - |
| Josh Shaw | ARI | DB | Shoulder | IR | IR | - | - | - | - | - |
| Robert Alford | ARI | DB | Leg | IR | IR | - | - | - | - | - |
| Hakeem Butler | ARI | WR | Finger | IR | IR | - | - | - | - | - |
| Ty Sambrailo | ATL | OL | Hamstring | In | In | - | - | LP | FP | FP |
| Younghoe Koo | ATL | K | Left foot | In | In | - | - | LP | LP | LP |
| Foyesade Oluokun | ATL | LB | Shoulder | In | In | - | - | LP | LP | LP |
| Isaiah Oliver | ATL | CB | Shoulder | In | In | - | - | LP | LP | LP |
| Ricardo Allen | ATL | S | Shoulder | In | In | - | - | LP | LP | LP |
| Julio Jones | ATL | WR | Shoulder | In | In | - | - | LP | LP | LP |
| Kenjon Barner | ATL | RB | Shoulder | In | In | - | - | DNP | LP | LP |
| Jamon Brown | ATL | G | Illness | In | In | - | - | DNP | LP | LP |
| Luke Stocker | ATL | TE | Hip | In | In | - | - | DNP | LP | LP |
| Jack Crawford | ATL | DL | Thigh | In | In | - | - | DNP | LP | LP |
| James Carpenter | ATL | OL | Concussion | IR | IR | - | - | - | - | - |
| Takk McKinley | ATL | DE | Shoulder | IR | IR | - | - | - | - | - |
| Desmond Trufant | ATL | CB | Forearm | IR | IR | - | - | - | - | - |
| Calvin Ridley | ATL | WR | Abdominal | IR | IR | - | - | - | - | - |
| Matt Bosher | ATL | P | Groin | IR | IR | - | - | - | - | - |
| Ito Smith | ATL | RB | Concussion | IR | IR | - | - | - | - | - |
| Keanu Neal | ATL | S | Achilles | IR | IR | - | - | - | - | - |
| Chris Lindstrom | ATL | G | Foot | IR | IR | - | - | - | - | - |
| Kurt Benkert | ATL | QB | Toe | IR | IR | - | - | - | - | - |
| J.J. Wilcox | ATL | DB | Knee | IR | IR | - | - | - | - | - |
| Michael Bennett | ATL | DL | Ankle | IR | IR | - | - | - | - | - |
| Steven Means | ATL | DL | Achilles | IR | IR | - | - | - | - | - |
| Chris Board | BAL | LB | Concussion | Ques | Prob | - | - | FP | FP | FP |
| Ronnie Stanley | BAL | LT | Concussion | Ques | Prob | - | - | FP | FP | FP |
| Matt Skura | BAL | C | Knee | IR | IR | - | - | - | - | - |
| Daylon Mack | BAL | DT | Knee, hip | IR | IR | - | - | - | - | - |
| Pernell McPhee | BAL | DE | Triceps | IR | IR | - | - | - | - | - |
| DeShon Elliott | BAL | S | Knee | IR | IR | - | - | - | - | - |
| Tony Jefferson | BAL | S | Knee | IR | IR | - | - | - | - | - |
| Tavon Young | BAL | DB | Neck | IR | IR | - | - | - | - | - |
| Ty Nsekhe | BUF | OT | Ankle | Out | Out | - | DNP | DNP | DNP | - |
| Corey Liuget | BUF | DT | Knee | Ques | Ques | - | LP | LP | LP | - |
| Harrison Phillips | BUF | DT | Knee | IR | IR | - | - | - | - | - |
| LaAdrian Waddle | BUF | T | Quad | IR | IR | - | - | - | - | - |
| Mike Love | BUF | DE | Pectoral | IR | IR | - | - | - | - | - |
| Jason Croom | BUF | TE | Hand | IR | IR | - | - | - | - | - |
| Vosean Joseph | BUF | LB | Undisclosed | IR | IR | - | - | - | - | - |
| Reggie Bonnafon | CAR | RB | Illness | In | In | - | - | DNP | FP | FP |
| Greg Olsen | CAR | TE | Concussion | In | In | - | - | FP | FP | FP |
| Marquis Haynes | CAR | LB | Knee | Out | Out | - | - | DNP | DNP | DNP |
| Garrett McGhin | CAR | OT | Ankle | Out | Out | - | - | DNP | DNP | DNP |
| Mario Addison | CAR | DE | Shoulder | In | In | - | - | DNP | DNP | FP |
| Gerald McCoy | CAR | DT | Knee | In | In | - | - | DNP | FP | FP |
| Eric Reid | CAR | S | Shoulder | In | In | - | - | DNP | FP | FP |
| Shaq Thompson | CAR | LB | Ankle | Out | Out | - | - | DNP | DNP | DNP |
| Vernon Butler | CAR | DT | Illness | Ques | Ques | - | - | FP | DNP | DNP |
| Curtis Samuel | CAR | WR | Knee | Ques | Ques | - | - | FP | LP | DNP |
| Greg Little | CAR | OT | Ankle | IR | IR | - | - | - | - | - |
| Jordan Scarlett | CAR | RB | Knee, ankle | IR | IR | - | - | - | - | - |
| Greg Van Roten | CAR | G | Leg | IR | IR | - | - | - | - | - |
| Dontari Poe | CAR | DT | Quad | IR | IR | - | - | - | - | - |
| Cam Newton | CAR | QB | Lisfranc | IR | IR | - | - | - | - | - |
| Natrell Jamerson | CAR | DB | Ankle | IR | IR | - | - | - | - | - |
| Chris Hogan | CAR | WR | Knee | IR | IR | - | - | - | - | - |
| Kawann Short | CAR | DT | Shoulder | IR | IR | - | - | - | - | - |
| Destiny Vaeao | CAR | DL | Quad | IR | IR | - | - | - | - | - |
| Graham Gano | CAR | K | Knee | IR | IR | - | - | - | - | - |
| Bobby Massie | CHI | RT | Ankle | Out | Out | - | - | DNP | DNP | DNP |
| Taylor Gabriel | CHI | WR | Concussion | Out | Out | - | - | DNP | DNP | DNP |
| Prince Amukamara | CHI | CB | Hamstring | Ques | Ques | - | - | FP | LP | LP |
| Bilal Nichols | CHI | DT | Knee | Ques | Ques | - | - | FP | FP | LP |
| Akiem Hicks | CHI | DT | Elbow | Ques | Ques | - | - | FP | FP | FP |
| Danny Trevathan | CHI | LB | Elbow | IR | IR | - | - | - | - | - |
| Ben Braunecker | CHI | TE | Concussion | IR | IR | - | - | - | - | - |
| Roquan Smith | CHI | LB | Pec | IR | IR | - | - | - | - | - |
| Sherrick McManis | CHI | S | Groin | IR | IR | - | - | - | - | - |
| Adam Shaheen | CHI | TE | Foot | IR | IR | - | - | - | - | - |
| Trey Burton | CHI | TE | Calf | IR | IR | - | - | - | - | - |
| T.J. Clemmings | CHI | G | Quad | IR | IR | - | - | - | - | - |
| AJ Green | CIN | WR | Ankle | Out | Out | - | - | DNP | DNP | DNP |
| Darius Phillips | CIN | CB | Hip | In | In | - | - | DNP | DNP | FP |
| Michael Jordan | CIN | G | Neck | In | In | - | - | FP | FP | FP |
| John Miller | CIN | RG | Concussion | Out | Out | - | - | DNP | DNP | DNP |
| Jonah Williams | CIN | T | Shoulder | PUP | PUP | - | - | - | - | - |
| Renell Wren | CIN | DT | Hip | IR | IR | - | - | - | - | - |
| Brandon Wilson | CIN | S | Hand | IR | IR | - | - | - | - | - |
| Auden Tate | CIN | WR | Leg | IR | IR | - | - | - | - | - |
| Alex Redmond | CIN | G | Biceps | IR | IR | - | - | - | - | - |
| Dre Kirkpatrick | CIN | CB | Knee | IR | IR | - | - | - | - | - |
| Kerry Wynn | CIN | DE | Concussion | IR | IR | - | - | - | - | - |
| Rodney Anderson | CIN | RB | Knee | IR | IR | - | - | - | - | - |
| Niles Scott | CIN | DT | Foot | IR | IR | - | - | - | - | - |
| Olivier Vernon | CLE | DL | Knee | Ques | Ques | - | - | LP | LP | LP |
| Eric Murray | CLE | CB | Knee | Ques | Ques | - | - | LP | LP | FP |
| Odell Beckham | CLE | WR | Groin | In | In | - | - | LP | LP | LP |
| Tae Davis | CLE | LB | Knee | In | In | - | - | LP | LP | FP |
| Dontrell Hilliard | CLE | RB | Neck | Ques | Ques | - | - | LP | LP | LP |
| Chris Hubbard | CLE | OT | Knee | In | In | - | - | LP | LP | LP |
| Kendall Lamm | CLE | OT | Knee | Ques | Ques | - | - | DNP | LP | LP |
| Jarvis Landry | CLE | WR | Hip | In | In | - | - | LP | LP | FP |
| Sheldon Richardson | CLE | DT | Back | Ques | Ques | - | - | DNP | DNP | LP |
| JC Tretter | CLE | C | Knee | Ques | Ques | - | - | DNP | DNP | LP |
| Denzel Ward | CLE | CB | Ankle | In | In | - | - | LP | LP | FP |
| Morgan Burnett | CLE | S | Achilles | IR | IR | - | - | - | - | - |
| Daniel Ekuale | CLE | DT | Calf | IR | IR | - | - | - | - | - |
| Willie Harvey | CLE | LB | Shoulder | IR | IR | - | - | - | - | - |
| Christian Kirksey | CLE | LB | Chest | IR | IR | - | - | - | - | - |
| David Njoku | CLE | TE | Wrist | IR | IR | - | - | - | - | - |
| Drew Stanton | CLE | QB | Knee | IR | IR | - | - | - | - | - |
| Drew Forbes | CLE | G | Knee | IR | IR | - | - | - | - | - |
| Phillip Gaines | CLE | DB | Concussion | IR | IR | - | - | - | - | - |
| Myles Garrett | CLE | DE | Indefinitely | Suspended | Suspended | - | - | - | - | - |
| Leighton Vander Esch | DAL | LB | Neck | Out | Out | - | - | DNP | DNP | DNP |
| Joe Thomas | DAL | LB | Knee | Ques | Ques | - | - | DNP | DNP | LP |
| Devin Smith | DAL | WR | Knee | Ques | Ques | - | - | FP | LP | LP |
| Michael Bennett | DAL | DE | Foot | In | In | - | - | DNP | LP | LP |
| La’el Collins | DAL | RT | Knee | In | In | - | - | LP | LP | LP |
| C.J. Goodwin | DAL | CB | Thumb | Ques | Ques | - | - | DNP | DNP | LP |
| Chris Jones | DAL | P | Abdomen | In | In | - | - | LP | LP | LP |
| Sean Lee | DAL | LB | Pec, thigh | In | In | - | - | DNP | LP | DNP |
| Jourdan Lewis | DAL | CB | Knee | In | In | - | - | LP | FP | FP |
| Dak Prescott | DAL | QB | Shoulder | In | In | - | - | LP | LP | LP |
| Tyron Smith | DAL | LT | Eye | In | In | - | - | DNP | LP | FP |
| Noah Brown | DAL | WR | Knee | PUP | PUP | - | - | - | - | - |
| Luke Gifford | DAL | LB | Arm | IR | IR | - | - | - | - | - |
| Cedrick Wilson | DAL | WR | Knee | IR | IR | - | - | - | - | - |
| Connor Williams | DAL | G | Knee | IR | IR | - | - | - | - | - |
| Anthony Brown | DAL | CB | Triceps | IR | IR | - | - | - | - | - |
| Tyrone Crawford | DAL | DT | Hip | IR | IR | - | - | - | - | - |
| Kavon Frazier | DAL | S | Pec | IR | IR | - | - | - | - | - |
| Jon’Vea Johnson | DAL | WR | Shoulder | IR | IR | - | - | - | - | - |
| David Irving | DAL | DL | Indefinitely | Suspended | Suspended | - | - | - | - | - |
| Randy Gregory | DAL | DL | Indefinitely | Suspended | Suspended | - | - | - | - | - |
| Ron Leary | DEN | OL | Concussion | Out | Out | - | - | DNP | DNP | DNP |
| Noah Fant | DEN | TE | Shoulder | Ques | Prob | - | - | LP | LP | LP |
| Adam Gotsis | DEN | DL | Knee | Out | Out | - | - | DNP | DNP | DNP |
| Ja’Wuan James | DEN | OL | Knee | Out | Out | - | - | DNP | DNP | DNP |
| Dre’Mont Jones | DEN | DL | Ankle | Ques | Ques | - | - | LP | LP | LP |
| Joe Jones | DEN | LB | Back | In | In | - | - | LP | LP | FP |
| DeMarcus Walker | DEN | DE | Ankle | Ques | Ques | - | - | DNP | LP | LP |
| Dalton Risner | DEN | OL | Illness | Ques | Ques | - | - | DNP | LP | DNP |
| Kyle Peko | DEN | NT | Illness | Ques | Ques | - | - | FP | DNP | LP |
| Juwann Winfree | DEN | WR | Hamstring | IR | IR | - | - | - | - | - |
| Derek Wolfe | DEN | DE | Elbow | IR | IR | - | - | - | - | - |
| Andy Janovich | DEN | FB | Elbow | IR | IR | - | - | - | - | - |
| Bryce Callahan | DEN | CB | Foot | IR | IR | - | - | - | - | - |
| Corey Nelson | DEN | LB | Biceps | IR | IR | - | - | - | - | - |
| Joe Flacco | DEN | QB | Neck | IR | IR | - | - | - | - | - |
| Bradley Chubb | DEN | OLB | Knee | IR | IR | - | - | - | - | - |
| Billy Winn | DEN | DL | Triceps | IR | IR | - | - | - | - | - |
| Drew Lock | DEN | QB | Thumb | IR | IR | - | - | - | - | - |
| Theo Riddick | DEN | RB | Shoulder | IR | IR | - | - | - | - | - |
| Jake Butt | DEN | TE | Knee | IR | IR | - | - | - | - | - |
| Austin Fort | DEN | TE | Knee | IR | IR | - | - | - | - | - |
| Nico Falah | DEN | C | Achilles | IR | IR | - | - | - | - | - |
| Kareem Jackson | DEN | S | 2 games | Suspended | Suspended | - | - | - | - | - |
| Devon Kennard | DET | LB | Hamstring | Ques | Ques | - | - | DNP | DNP | LP |
| A’Shawn Robinson | DET | DL | Shoulder | Out | Out | - | - | DNP | DNP | DNP |
| Rick Wagner | DET | OL | Knee | Out | Out | - | - | LP | LP | DNP |
| Christian Jones | DET | LB | Shoulder | Out | Out | - | - | LP | LP | DNP |
| Bo Scarbrough | DET | RB | Ribs | Ques | Ques | - | - | LP | LP | LP |
| Matthew Stafford | DET | QB | Hip/Back | IR | IR | - | - | - | - | - |
| Mike Daniels | DET | DT | Arm | IR | IR | - | - | - | - | - |
| Kenny Wiggins | DET | G | Arm | IR | IR | - | - | - | - | - |
| Joe Dahl | DET | OL | Back/Knee | IR | IR | - | - | - | - | - |
| Jarrad Davis | DET | LB | Ankle/Knee | IR | IR | - | - | - | - | - |
| Marvin Jones | DET | WR | Ankle | IR | IR | - | - | - | - | - |
| Da’shawn Hand | DET | DL | Ankle | IR | IR | - | - | - | - | - |
| Marvin Hall | DET | WR | Foot | IR | IR | - | - | - | - | - |
| Jeff Driskel | DET | QB | Hamstring | IR | IR | - | - | - | - | - |
| T.J. Hockenson | DET | TE | Ankle | IR | IR | - | - | - | - | - |
| Nick Bawden | DET | FB | Knee | IR | IR | - | - | - | - | - |
| Kevin Strong | DET | DT | Rib | IR | IR | - | - | - | - | - |
| Tra Carson | DET | RB | Hamstring | IR | IR | - | - | - | - | - |
| Kerryon Johnson | DET | RB | Knee | IR | IR | - | - | - | - | - |
| Austin Bryant | DET | DE | Pectorals | IR | IR | - | - | - | - | - |
| Jermaine Kearse | DET | WR | Leg | IR | IR | - | - | - | - | - |
| Jimmy Graham | GNB | TE | Wrist, groin | - | Prob | - | - | - | LP | LP |
| Alex Light | GNB | OT | Illness | - | Prob | - | - | - | DNP | FP |
| Dean Lowry | GNB | DL | Ankle | - | Ques | - | - | - | LP | LP |
| Blake Martinez | GNB | LB | Hand, calf | - | Ques | - | - | - | LP | LP |
| Yosh Nijman | GNB | OT | Elbow | - | Ques | - | - | - | FP | LP |
| Cole Madison | GNB | G | Knee | IR | IR | - | - | - | - | - |
| Lane Taylor | GNB | G | Biceps | IR | IR | - | - | - | - | - |
| Raven Greene | GNB | LB | Ankle | IR | IR | - | - | - | - | - |
| Jace Sternberger | GNB | TE | Ankle | IR | IR | - | - | - | - | - |
| Equanimeous St. Brown | GNB | WR | Ankle | IR | IR | - | - | - | - | - |
| Jason Spriggs | GNB | T | Abdomen | IR | IR | - | - | - | - | - |
| Taiwan Jones | HOU | RB | Hamstring | Ques | Ques | - | LP | LP | LP | - |
| Benardrick McKinney | HOU | LB | Concussion | Out | Out | - | DNP | DNP | DNP | - |
| Jahleel Addae | HOU | S | Achilles | Ques | Ques | - | DNP | LP | LP | - |
| Jacob Martin | HOU | OLB | Knee | Out | Out | - | DNP | DNP | DNP | - |
| Darren Fells | HOU | TE | Hand | In | In | - | LP | LP | FP | - |
| Will Fuller | HOU | WR | Hamstring | Ques | Prob | - | LP | LP | LP | - |
| Carlos Hyde | HOU | RB | Ankle, NIR | Ques | Prob | - | LP | DNP | LP | - |
| Brennan Scarlett | HOU | OLB | Achilles | Ques | Ques | - | LP | LP | LP | - |
| DeAndre Hopkins | HOU | WR | Illness | In | In | - | FP | DNP | FP | - |
| Tytus Howard | HOU | OT | Knee | IR | IR | - | - | - | - | - |
| Dylan Cole | HOU | LB | Knee | IR | IR | - | - | - | - | - |
| J.J. Watt | HOU | DT | Pec | IR | IR | - | - | - | - | - |
| Phillip Gaines | HOU | CB | Ankle | IR | IR | - | - | - | - | - |
| Kahale Warring | HOU | TE | Concussion | IR | IR | - | - | - | - | - |
| Jordan Thomas | HOU | TE | Rib | IR | IR | - | - | - | - | - |
| Lamar Miller | HOU | RB | Knee | IR | IR | - | - | - | - | - |
| Joe Webb | HOU | QB | Foot | IR | IR | - | - | - | - | - |
| Duke Ejiofor | HOU | DL | Achilles | IR | IR | - | - | - | - | - |
| Quincy Wilson | IND | CB | Shoulder | Out | Out | - | - | DNP | DNP | DNP |
| Denico Autry | IND | DT | Concussion | Out | Out | - | - | DNP | DNP | DNP |
| Kenny Moore | IND | S | Ankle | Out | Out | - | - | DNP | DNP | DNP |
| Malik Hooker | IND | S | Hand | Ques | Ques | - | - | DNP | DNP | FP |
| Anthony Walker | IND | LB | Hamstring | In | In | - | - | LP | LP | FP |
| Rolan Milligan | IND | S | Foot | IR | IR | - | - | - | - | - |
| Parris Campbell | IND | WR | Foot | IR | IR | - | - | - | - | - |
| Adam Vinatieri | IND | K | Knee | IR | IR | - | - | - | - | - |
| Chester Rogers | IND | WR | Knee | IR | IR | - | - | - | - | - |
| Eric Ebron | IND | TE | Ankle | IR | IR | - | - | - | - | - |
| Kemoko Turay | IND | DE | Ankle | IR | IR | - | - | - | - | - |
| Devin Funchess | IND | WR | Collarbone | IR | IR | - | - | - | - | - |
| Daurice Fountain | IND | WR | Leg | IR | IR | - | - | - | - | - |
| Javon Patterson | IND | G | Knee | IR | IR | - | - | - | - | - |
| D.J. Chark | JAX | WR | Foot | Ques | Prob | - | - | LP | LP | LP |
| Josh Allen | JAX | DE | Shoulder | In | In | - | - | LP | LP | LP |
| Gardner Minshew | JAX | QB | Shoulder | In | In | - | - | LP | LP | FP |
| D.J. Hayden | JAX | CB | Knee | In | In | - | - | LP | LP | LP |
| Austin Calitro | JAX | LB | Shoulder | In | In | - | - | LP | LP | FP |
| Brandon Linder | JAX | OL | Knee | In | In | - | - | DNP | LP | FP |
| Cam Robinson | JAX | OL | Knee | In | In | - | - | LP | LP | FP |
| Nick O’Leary | JAX | TE | Shoulder | In | In | - | - | LP | LP | FP |
| Calais Campbell | JAX | DL | Back | In | In | - | - | DNP | LP | FP |
| Abry Jones | JAX | DT | Elbow | In | In | - | - | LP | LP | FP |
| A.J. Bouye | JAX | CB | Hamstring | In | In | - | - | LP | LP | FP |
| Lerentee McCray | JAX | DE | Hamstring | NFI | NFI | - | - | - | - | - |
| Jake Ryan | JAX | LB | Hamstring | IR | IR | - | - | - | - | - |
| Quincy Williams | JAX | LB | Hand | IR | IR | - | - | - | - | - |
| Myles Jack | JAX | LB | Knee | IR | IR | - | - | - | - | - |
| Josh Oliver | JAX | TE | Back | IR | IR | - | - | - | - | - |
| Marqise Lee | JAX | WR | Shoulder | IR | IR | - | - | - | - | - |
| Marcell Dareus | JAX | DT | Abdominal | IR | IR | - | - | - | - | - |
| Geoff Swaim | JAX | TE | Concussion | IR | IR | - | - | - | - | - |
| James O’Shaughnessy | JAX | TE | Knee | IR | IR | - | - | - | - | - |
| Jake Ryan | JAX | LB | Knee | IR | IR | - | - | - | - | - |
| Telvin Smith | JAX | LB | Personal | IR | IR | - | - | - | - | - |
| James Onwualu | JAX | LB | Knee | IR | IR | - | - | - | - | - |
| Ben Ijalana | JAX | G | Elbow | IR | IR | - | - | - | - | - |
| Damien Williams | KAN | RB | Ribs | In | In | - | - | LP | LP | FP |
| Rashad Fenton | KAN | CB | Hamstring | In | In | - | - | LP | FP | FP |
| Morris Claiborne | KAN | CB | Shoulder | Out | Out | - | - | LP | LP | LP |
| Andrew Wylie | KAN | G | Ankle | Out | Out | - | - | DNP | DNP | DNP |
| Alex Okafor | KAN | DE | Chest | IR | IR | - | - | - | - | - |
| Darrel Williams | KAN | RB | Hamstring | IR | IR | - | - | - | - | - |
| Emmanuel Ogbah | KAN | DE | Pec | IR | IR | - | - | - | - | - |
| Martinas Rankin | KAN | RG | Knee | IR | IR | - | - | - | - | - |
| Breeland Speaks | KAN | LB | Knee | IR | IR | - | - | - | - | - |
| Marcus Kemp | KAN | WR | Knee | IR | IR | - | - | - | - | - |
| Chad Henne | KAN | QB | Ankle | IR | IR | - | - | - | - | - |
| Keith Reaser | KAN | DB | Achilles | IR | IR | - | - | - | - | - |
| Russell Okung | LAC | LT | Groin | Doub | Doub | - | - | DNP | DNP | DNP |
| Justin Jackson | LAC | RB | Hamstring | Ques | Ques | - | - | LP | LP | LP |
| Mike Williams | LAC | WR | Knee | In | In | - | - | LP | FP | FP |
| Cortez Broughton | LAC | DT | Illness | NFI | NFI | - | - | - | - | - |
| Geremy Davis | LAC | WR | Hamstring | IR | IR | - | - | - | - | - |
| Forrest Lamp | LAC | G | Ankle | IR | IR | - | - | - | - | - |
| Travis Benjamin | LAC | WR | Quad | IR | IR | - | - | - | - | - |
| Mike Pouncey | LAC | C | Neck | IR | IR | - | - | - | - | - |
| Adrian Phillips | LAC | S | Forearm | IR | IR | - | - | - | - | - |
| Derwin James | LAC | S | Foot | IR | IR | - | - | - | - | - |
| Greg Zuerlein | LAR | K | Right quad | Ques | Ques | - | DNP | DNP | DNP | - |
| Gerald Everett | LAR | TE | Knee | In | In | - | LP | FP | FP | - |
| Troy Hill | LAR | CB | Thumb | Out | Out | - | DNP | DNP | DNP | - |
| Bryce Hager | LAR | LB | Shoulder | IR | IR | - | - | - | - | - |
| Brian Allen | LAR | C | Knee | IR | IR | - | - | - | - | - |
| John Johnson | LAR | S | Shoulder | IR | IR | - | - | - | - | - |
| Joe Noteboom | LAR | LG | Knee | IR | IR | - | - | - | - | - |
| Justin Lawler | LAR | LB | Foot | IR | IR | - | - | - | - | - |
| Micah Kiser | LAR | LB | Pectorals | IR | IR | - | - | - | - | - |
| Chandler Cox | MIA | FB | Shoulder | Ques | Ques | - | - | LP | FP | FP |
| Allen Hurns | MIA | WR | Ankle, knee | In | In | - | - | LP | LP | LP |
| Nik Needham | MIA | CB | Groin | In | In | - | - | LP | FP | FP |
| DeVante Parker | MIA | WR | Hip | In | In | - | - | LP | FP | FP |
| Zach Sieler | MIA | DT | Ankle | Ques | Ques | - | - | LP | LP | LP |
| Albert Wilson | MIA | WR | Hip | In | In | - | - | LP | FP | FP |
| Jason Sanders | MIA | K | Illness | Ques | Ques | - | - | FP | LP | LP |
| Evan Boehm | MIA | C | Ankle | Ques | Ques | - | - | FP | FP | LP |
| Taco Charlton | MIA | DE | Ankle | Ques | Ques | - | - | FP | FP | LP |
| Cordrea Tankersley | MIA | DB | Knee | PUP | PUP | - | - | - | - | - |
| Mike Hull | MIA | LB | Knee | PUP | PUP | - | - | - | - | - |
| Raekwon McMillan | MIA | LB | Hamstring | IR | IR | - | - | - | - | - |
| Ken Webster | MIA | CB | Undisclosed | IR | IR | - | - | - | - | - |
| Ken Crawley | MIA | CB | Shoulder | IR | IR | - | - | - | - | - |
| Kalen Ballage | MIA | RB | Leg | IR | IR | - | - | - | - | - |
| Jakeem Grant | MIA | WR | Ankle | IR | IR | - | - | - | - | - |
| Preston Williams | MIA | WR | Knee | IR | IR | - | - | - | - | - |
| James Crawford | MIA | LB | Knee | IR | IR | - | - | - | - | - |
| Jonathan Ledbetter | MIA | DE | Ankle | IR | IR | - | - | - | - | - |
| Ricardo Louis | MIA | WR | Neck | IR | IR | - | - | - | - | - |
| Alexander Mattison | MIN | RB | Ankle | - | Ques | - | - | - | DNP | DNP |
| Dalvin Cook | MIN | RB | Shoulder | - | Ques | - | - | - | DNP | DNP |
| Jayron Kearse | MIN | S | Toe | - | Prob | - | - | - | FP | FP |
| David Morgan | MIN | TE | Knee | PUP | PUP | - | - | - | - | - |
| Ben Gedeon | MIN | LB | Concussion | IR | IR | - | - | - | - | - |
| Ben Gedeon | MIN | LB | Concussion | IR | IR | - | - | - | - | - |
| Brett Jones | MIN | C | Knee | IR | IR | - | - | - | - | - |
| Chad Beebe | MIN | WR | Ankle | IR | IR | - | - | - | - | - |
| Josh Doctson | MIN | WR | Leg | IR | IR | - | - | - | - | - |
| Tashawn Bower | MIN | DL | Achilles | IR | IR | - | - | - | - | - |
| Andrus Peat | NOR | G | Arm | Ques | Prob | - | - | LP | LP | LP |
| Patrick Robinson | NOR | CB | Calf | Ques | Ques | - | - | LP | LP | FP |
| Kiko Alonso | NOR | LB | Thigh | Out | Out | - | - | LP | LP | DNP |
| Larry Warford | NOR | RG | Knee | Out | Out | - | - | DNP | DNP | DNP |
| C.J. Gardner Johnson | NOR | CB | Concussion | Ques | Ques | - | - | DNP | LP | FP |
| Ryan Ramczyk | NOR | OT | Knee | In | In | - | - | LP | LP | FP |
| Vonn Bell | NOR | S | Knee | Out | Out | - | - | DNP | DNP | DNP |
| Terron Armstead | NOR | LT | Ankle | In | In | - | - | LP | LP | FP |
| Marcus Davenport | NOR | DE | Foot | IR | IR | - | - | - | - | - |
| Sheldon Rankins | NOR | DT | Achilles | IR | IR | - | - | - | - | - |
| Jason Vander Laan | NOR | TE | Head | IR | IR | - | - | - | - | - |
| Keith Kirkwood | NOR | WR | Hamstring | IR | IR | - | - | - | - | - |
| Josh Martin | NOR | LB | Shoulder | IR | IR | - | - | - | - | - |
| Garrett Griffin | NOR | TE | Leg | IR | IR | - | - | - | - | - |
| Julian Edelman | NWE | WR | Knee, shoulder | Ques | Prob | - | LP | LP | LP | - |
| Jason McCourty | NWE | CB | Groin | Ques | Ques | - | LP | LP | LP | - |
| Ja’whaun Bentley | NWE | LB | Knee | Ques | Ques | - | LP | LP | LP | - |
| Jonathan Jones | NWE | CB | Groin | Out | Out | - | DNP | DNP | DNP | - |
| Danny Shelton | NWE | DL | Shoulder | In | In | - | LP | LP | FP | - |
| Jamie Collins | NWE | LB | Shoulder | Ques | Ques | - | FP | LP | LP | - |
| Gunner Olszewski | NWE | WR | Hamstring | IR | IR | - | - | - | - | - |
| Jakob Johnson | NWE | FB | Shoulder | IR | IR | - | - | - | - | - |
| James Develin | NWE | FB | Neck | IR | IR | - | - | - | - | - |
| Stephen Gostkowski | NWE | K | Hip | IR | IR | - | - | - | - | - |
| Isaiah Wynn | NWE | LT | Foot | IR | IR | - | - | - | - | - |
| Yodny Cajuste | NWE | T | Quad | IR | IR | - | - | - | - | - |
| Hjalte Froholdt | NWE | G | Shoulder | IR | IR | - | - | - | - | - |
| Brandon King | NWE | DB | Leg | IR | IR | - | - | - | - | - |
| David Andrews | NWE | C | Illness | IR | IR | - | - | - | - | - |
| Malik Gant | NWE | DB | Leg | IR | IR | - | - | - | - | - |
| Rhett Ellison | NYG | TE | Concussion | Out | Out | - | - | FP | LP | LP |
| Daniel Jones | NYG | QB | Ankle | In | In | - | - | FP | FP | FP |
| Kevin Zeitler | NYG | OL | Ankle/Wrist | In | In | - | - | LP | LP | FP |
| Antoine Bethea | NYG | S | NIR | In | In | - | - | DNP | DNP | FP |
| Evan Engram | NYG | TE | Foot | IR | IR | - | - | - | - | - |
| Jabrill Peppers | NYG | S | Back | IR | IR | - | - | - | - | - |
| Ryan Connelly | NYG | LB | Knee | IR | IR | - | - | - | - | - |
| Russell Shepard | NYG | WR | Foot | IR | IR | - | - | - | - | - |
| Kareem Martin | NYG | LB | Knee | IR | IR | - | - | - | - | - |
| Jonathan Anderson | NYG | LB | Knee | IR | IR | - | - | - | - | - |
| Corey Coleman | NYG | WR | Knee | IR | IR | - | - | - | - | - |
| Rod Smith | NYG | RB | Hip | IR | IR | - | - | - | - | - |
| Sam Beal | NYG | CB | Hamstring | IR | IR | - | - | - | - | - |
| Scott Simonson | NYG | TE | Ankle | IR | IR | - | - | - | - | - |
| Tom Compton | NYJ | OL | Calf | Doub | Doub | - | - | DNP | DNP | DNP |
| Quinnen Williams | NYJ | DL | Stinger | Ques | Ques | - | - | LP | LP | LP |
| Demaryius Thomas | NYJ | WR | Hamstring | Doub | Doub | - | - | DNP | DNP | DNP |
| Brian Poole | NYJ | CB | Concussion | Ques | Ques | - | - | LP | LP | LP |
| Jamal Adams | NYJ | S | Ankle | Ques | Prob | - | - | LP | LP | LP |
| Arthur Maulet | NYJ | CB | Calf | Ques | Ques | - | - | LP | LP | LP |
| Bilal Powell | NYJ | RB | Ankle | Ques | Ques | - | - | LP | LP | LP |
| Henry Anderson | NYJ | DL | Shoulder | Ques | Prob | - | - | LP | LP | LP |
| Kelvin Beachum | NYJ | OT | Ankles | Ques | Prob | - | - | LP | LP | LP |
| Robby Anderson | NYJ | WR | Illness | Ques | Prob | - | - | FP | DNP | LP |
| B.J. Bello | NYJ | LB | Illness | In | In | - | - | LP | FP | FP |
| Bennett Jackson | NYJ | S | Illness | In | In | - | - | LP | LP | FP |
| Steve McLendon | NYJ | DL | Knee, hip | Ques | Prob | - | - | LP | LP | LP |
| Jeff Smith | NYJ | WR | Ankle | IR | IR | - | - | - | - | - |
| Chuma Edoga | NYJ | RT | Knee | IR | IR | - | - | - | - | - |
| Ryan Griffin | NYJ | TE | Ankle | IR | IR | - | - | - | - | - |
| Kyron Brown | NYJ | CB | Quad | IR | IR | - | - | - | - | - |
| CJ Mosley | NYJ | LB | Groin | IR | IR | - | - | - | - | - |
| Ryan Kalil | NYJ | C | Knee | IR | IR | - | - | - | - | - |
| Brian Winters | NYJ | G | Elbow | IR | IR | - | - | - | - | - |
| Chris Herndon | NYJ | TE | Ribs | IR | IR | - | - | - | - | - |
| Albert McClellan | NYJ | LB | Concussion | IR | IR | - | - | - | - | - |
| Trenton Cannon | NYJ | RB | Foot, ankle | IR | IR | - | - | - | - | - |
| John Franklin-Myers | NYJ | DL | Undisclosed | IR | IR | - | - | - | - | - |
| Trevor Siemian | NYJ | QB | Ankle | IR | IR | - | - | - | - | - |
| Quincy Enunwa | NYJ | WR | Neck | IR | IR | - | - | - | - | - |
| Avery Williamson | NYJ | LB | Knee | IR | IR | - | - | - | - | - |
| Brent Qvale | NYJ | T | Knee | IR | IR | - | - | - | - | - |
| Josh Jacobs | OAK | RB | Shoulder | Out | Out | - | - | DNP | DNP | DNP |
| Hunter Renfrow | OAK | WR | Ribs | In | In | - | - | LP | LP | FP |
| Kyle Wilber | OAK | LB | Ankle | In | In | - | - | LP | LP | FP |
| Daryl Worley | OAK | CB | Neck | In | In | - | - | LP | LP | FP |
| Rodney Hudson | OAK | C | Ankle | In | In | - | - | LP | LP | LP |
| Richie Incognito | OAK | G | Ankle | Out | Out | - | - | DNP | DNP | DNP |
| Gabe Jackson | OAK | G | Knee | In | In | - | - | LP | DNP | LP |
| Nevin Lawson | OAK | CB | Biceps | In | In | - | - | LP | LP | FP |
| Dallin Leavitt | OAK | S | Elbow | In | In | - | - | LP | LP | FP |
| Marquel Lee | OAK | LB | Toe | Out | Out | - | - | DNP | DNP | DNP |
| Trent Brown | OAK | OT | Pectoral | IR | IR | - | - | - | - | - |
| Foster Moreau | OAK | TE | Knee | IR | IR | - | - | - | - | - |
| Dwayne Harris | OAK | WR | Ankle | IR | IR | - | - | - | - | - |
| Karl Joseph | OAK | S | Foot | IR | IR | - | - | - | - | - |
| Arden Key | OAK | DE | Foot | IR | IR | - | - | - | - | - |
| Jordan Devey | OAK | G | Pec | IR | IR | - | - | - | - | - |
| Jonathan Abram | OAK | S | Shoulder | IR | IR | - | - | - | - | - |
| Justin Ellis | OAK | DL | Knee | IR | IR | - | - | - | - | - |
| Nathan Peterman | OAK | QB | Elbow | IR | IR | - | - | - | - | - |
| Isaiah Crowell | OAK | RB | Achilles | IR | IR | - | - | - | - | - |
| Vontaze Burfict | OAK | LB | Season | Suspended | Suspended | - | - | - | - | - |
| Jordan Howard | PHI | RB | Shoulder | Ques | Doub | - | - | LP | LP | LP |
| Nelson Agholor | PHI | WR | Knee | Ques | Doub | - | - | DNP | DNP | DNP |
| Lane Johnson | PHI | RT | Ankle | Out | Out | - | - | DNP | DNP | DNP |
| Derek Barnett | PHI | DE | Ankle | Ques | Ques | - | - | DNP | LP | LP |
| Avonte Maddox | PHI | CB | Knee | Ques | Ques | - | - | FP | LP | LP |
| Brandon Brooks | PHI | G | Calf | In | In | - | - | LP | FP | FP |
| Fletcher Cox | PHI | DT | Triceps | In | In | - | - | LP | FP | FP |
| Ronald Darby | PHI | CB | Hip | In | In | - | - | LP | FP | FP |
| Kamu Grugier-Hill | PHI | LB | Back | IR | IR | - | - | - | - | - |
| Alshon Jeffery | PHI | WR | Foot | IR | IR | - | - | - | - | - |
| Rudy Ford | PHI | S | Abdomen | IR | IR | - | - | - | - | - |
| Darren Sproles | PHI | RB | Quad | IR | IR | - | - | - | - | - |
| DeSean Jackson | PHI | WR | Abdomen | IR | IR | - | - | - | - | - |
| Corey Clement | PHI | RB | Shoulder | IR | IR | - | - | - | - | - |
| Jordan Mailata | PHI | T | Back | IR | IR | - | - | - | - | - |
| Malik Jackson | PHI | DT | Foot | IR | IR | - | - | - | - | - |
| Cre’von LeBlanc | PHI | DB | Foot | IR | IR | - | - | - | - | - |
| Charles Johnson | PHI | WR | Ankle | IR | IR | - | - | - | - | - |
| Vance McDonald | PIT | TE | Concussion | In | In | - | - | FP | FP | FP |
| JuJu Smith-Schuster | PIT | WR | Knee | In | In | - | - | LP | FP | FP |
| Artie Burns | PIT | CB | Illness | In | In | - | - | DNP | FP | FP |
| Ryan Shazier | PIT | LB | Back | PUP | PUP | - | - | - | - | - |
| Ryan Switzer | PIT | WR | Back | IR | IR | - | - | - | - | - |
| Roosevelt Nix | PIT | FB | Knee | IR | IR | - | - | - | - | - |
| Stephon Tuitt | PIT | DT | Pec | IR | IR | - | - | - | - | - |
| Ben Roethlisberger | PIT | QB | Elbow | IR | IR | - | - | - | - | - |
| Sean Davis | PIT | S | Shoulder | IR | IR | - | - | - | - | - |
| Luke Willson | SEA | TE | Hamstring | In | In | - | - | FP | LP | LP |
| Mychal Kendricks | SEA | LB | Hamstring | Ques | Ques | - | - | LP | DNP | DNP |
| Jadeveon Clowney | SEA | DL | Core | Doub | Doub | - | - | DNP | DNP | DNP |
| Ziggy Ansah | SEA | DE | Neck | In | In | - | - | FP | FP | FP |
| Shaquill Griffin | SEA | CB | Hamstring | Ques | Ques | - | - | LP | DNP | DNP |
| Quandre Diggs | SEA | S | Ankle | Doub | Doub | - | - | DNP | DNP | DNP |
| Bobby Wagner | SEA | LB | Ankle | In | In | - | - | DNP | DNP | DNP |
| Duane Brown | SEA | OT | Biceps, knee | Ques | Ques | - | - | DNP | DNP | DNP |
| George Fant | SEA | OT | Illness | In | In | - | - | DNP | FP | FP |
| Joey Hunt | SEA | C | Fibula | In | In | - | - | LP | LP | LP |
| Cody Barton | SEA | LB | Thigh | In | In | - | - | LP | FP | FP |
| Mike Iupati | SEA | G | Neck | In | In | - | - | LP | LP | LP |
| Rashaad Penny | SEA | RB | Knee | IR | IR | - | - | - | - | - |
| Justin Britt | SEA | C | Knee | IR | IR | - | - | - | - | - |
| Will Dissly | SEA | TE | Achilles | IR | IR | - | - | - | - | - |
| Jordan Simmons | SEA | G | Knee | IR | IR | - | - | - | - | - |
| Nazair Jones | SEA | DL | Knee | IR | IR | - | - | - | - | - |
| Josh Gordon | SEA | WR | Indefinitely | Suspended | Suspended | - | - | - | - | - |
| Al Woods | SEA | DT | 4 games | Suspended | Suspended | - | - | - | - | - |
| Mike Person | SFO | OL | Neck | Ques | Ques | - | LP | LP | LP | - |
| Richard Sherman | SFO | CB | Hamstring | In | In | - | FP | FP | FP | - |
| Jaquiski Tartt | SFO | S | Rib | Out | Out | - | DNP | DNP | DNP | - |
| Jullian Taylor | SFO | DT | Elbow | Out | Out | - | DNP | DNP | LP | - |
| Dee Ford | SFO | DE | Hamstring | Out | Out | - | DNP | DNP | DNP | - |
| K’Waun Williams | SFO | CB | Concussion | In | In | - | FP | FP | FP | - |
| DJ Jones | SFO | DT | Ankle | IR | IR | - | - | - | - | - |
| Marquise Goodwin | SFO | WR | Knee, foot | IR | IR | - | - | - | - | - |
| Weston Richburg | SFO | C | Knee, ankle | IR | IR | - | - | - | - | - |
| Ronald Blair | SFO | DT | Knee | IR | IR | - | - | - | - | - |
| Kwon Alexander | SFO | LB | Pec | IR | IR | - | - | - | - | - |
| Jalen Hurd | SFO | WR | Back | IR | IR | - | - | - | - | - |
| Trent Taylor | SFO | WR | Foot | IR | IR | - | - | - | - | - |
| Kentavius Street | SFO | DT | Knee | IR | IR | - | - | - | - | - |
| Jerick McKinnon | SFO | RB | Knee | IR | IR | - | - | - | - | - |
| Shon Coleman | SFO | T | Ankle | IR | IR | - | - | - | - | - |
| Tim Harris | SFO | DB | Groin | IR | IR | - | - | - | - | - |
| Beau Allen | TAM | NT | Ankle | Out | Out | - | DNP | DNP | DNP | - |
| Anthony Nelson | TAM | OLB | Hamstring | In | In | - | FP | FP | FP | - |
| Chris Godwin | TAM | WR | Hamstring | Out | Out | - | DNP | DNP | DNP | - |
| Tanner Hudson | TAM | TE | Concussion | Out | Out | - | DNP | DNP | DNP | - |
| Donovan Smith | TAM | OT | Ankle, knee | Ques | Ques | - | DNP | LP | LP | - |
| Matt Gay | TAM | K | Groin | In | In | - | LP | LP | FP | - |
| Carlton Davis | TAM | CB | Ankle | Ques | Ques | - | FP | FP | LP | - |
| Ryan Jensen | TAM | C | Elbow | Ques | Prob | - | LP | FP | FP | - |
| Jameis Winston | TAM | QB | Right thumb | Ques | Prob | - | LP | LP | FP | - |
| Jordan Whitehead | TAM | S | Hamstring | IR | IR | - | - | - | - | - |
| Scotty Miller | TAM | WR | Hamstring | IR | IR | - | - | - | - | - |
| Mike Evans | TAM | WR | Hamstring | IR | IR | - | - | - | - | - |
| T.J. Logan | TAM | RB | Thumb | IR | IR | - | - | - | - | - |
| Jack Cichy | TAM | LB | Elbow | IR | IR | - | - | - | - | - |
| Blaine Gabbert | TAM | QB | Shoulder | IR | IR | - | - | - | - | - |
| Justin Evans | TAM | S | Achilles | IR | IR | - | - | - | - | - |
| Kendell Beckwith | TAM | LB | Ankle | IR | IR | - | - | - | - | - |
| Michael Liedtke | TAM | OL | Shoulder | IR | IR | - | - | - | - | - |
| Orion Stewart | TAM | DB | Knee | IR | IR | - | - | - | - | - |
| Adoree’ Jackson | TEN | CB | Knee | Out | Out | - | - | LP | DNP | DNP |
| Adam Humphries | TEN | WR | Ankle | Out | Out | - | - | DNP | DNP | DNP |
| Jeffery Simmons | TEN | DL | Knee | Ques | Ques | - | - | FP | FP | DNP |
| Daren Bates | TEN | LB | Shoulder | In | In | - | - | LP | FP | FP |
| Corey Davis | TEN | WR | Ankle | In | In | - | - | LP | FP | FP |
| Derrick Henry | TEN | RB | Hamstring | In | In | - | - | LP | DNP | FP |
| Kalif Raymond | TEN | WR | Knee | In | In | - | - | LP | FP | FP |
| Wesley Woodyard | TEN | LB | Knee | In | In | - | - | LP | FP | FP |
| Ryan Succop | TEN | K | Knee | IR | IR | - | - | - | - | - |
| Delanie Walker | TEN | TE | Ankle | IR | IR | - | - | - | - | - |
| Malcolm Butler | TEN | CB | Wrist | IR | IR | - | - | - | - | - |
| David Fluellen | TEN | RB | Knee | IR | IR | - | - | - | - | - |
| Ryan Succop | TEN | K | Knee | IR | IR | - | - | - | - | - |
| Joshua Kalu | TEN | CB | Undisclosed | IR | IR | - | - | - | - | - |
| Cameron Batson | TEN | WR | Upper Body | IR | IR | - | - | - | - | - |
| Landon Collins | WAS | S | Achilles | Ques | Ques | - | - | DNP | DNP | FP |
| Quinton Dunbar | WAS | CB | Hamstring | Out | Out | - | - | LP | DNP | DNP |
| Jonathan Allen | WAS | DL | Toe | In | In | - | - | LP | LP | FP |
| Montae Nicholson | WAS | S | Ankle | In | In | - | - | LP | LP | FP |
| Donald Penn | WAS | OT | Knee | In | In | - | - | LP | LP | FP |
| Fabian Moreau | WAS | CB | Hamstring | Doub | Doub | - | - | DNP | DNP | DNP |
| Ryan Kerrigan | WAS | LB | Calf | IR | IR | - | - | - | - | - |
| Brandon Scherff | WAS | OL | Shoulder | IR | IR | - | - | - | - | - |
| Trey Quinn | WAS | WR | Concussion | IR | IR | - | - | - | - | - |
| Jimmy Moreland | WAS | CB | Foot | IR | IR | - | - | - | - | - |
| Paul Richardson | WAS | WR | Hamstring | IR | IR | - | - | - | - | - |
| Derrius Guice | WAS | RB | Knee | IR | IR | - | - | - | - | - |
| Vernon Davis | WAS | TE | Concussion | IR | IR | - | - | - | - | - |
| Jordan Reed | WAS | TE | Concussion | IR | IR | - | - | - | - | - |
| Dominique Rodgers-Cromartie | WAS | CB | Ankle | IR | IR | - | - | - | - | - |
| Derrius Guice | WAS | RB | Knee | IR | IR | - | - | - | - | - |
| Caleb Brantley | WAS | DL | Ankle | IR | IR | - | - | - | - | - |
| Bryce Love | WAS | RB | Knee | IR | IR | - | - | - | - | - |
| Josh Woodrum | WAS | QB | Pectorals | IR | IR | - | - | - | - | - |
| Alex Smith | WAS | QB | Leg | IR | IR | - | - | - | - | - |
| Reuben Foster | WAS | LB | Knee | IR | IR | - | - | - | - | - |
