Watch Now

Week 16 preview: Colts vs. Cardinals

December 23, 2021 02:01 PM

Chris Simms and Mike Florio preview the critical Week 16 matchup between the Indianapolis Colts and Arizona Cardinals and discuss if the Cardinals can prove they are true contenders in the NFC following a two-game skid.

Related Videos

Anderson: Texans D-line a group of ‘alpha dogs’

Fill in the blank: Best man CB, edge rusher in NFL

PFT Draft: Rookies we can’t wait to see Week 1

Ward’s mechanics won’t need any dramatic changes

49ers have confidence Jones can be NFL starter

How Jags are splitting Hunter’s workload so far

Graham vomited during day two of rookie minicamp

Scale of 1-10: Doing deals before training camp

Eagles-Packers to square off on MNF in Week 10

CIN has ‘nothing to stand on’ in Hendrickson issue

How bad teams benefit from consistent scheduling

Kickoff, Christmas night among 2025 games revealed

Carr’s retirement opens the door for Shough

Evaluating Sanders’ motivation amid QB competition

Saints don’t have ‘proven commodity’ in QB room

Cowboys to start ‘new era’ against Eagles

Carr’s NFL career arc ‘rare’ for a starting QB

Stewart, Knight skip Bengals’ rookie minicamp

Rodgers decision could come sooner than later

Khan expresses confidence in Steelers’ receivers

Khan wanted ‘fresh start’ for Pickens, Steelers

Dart ready to earn opportunity to start

Sanders: My job is to ‘prove myself right’

Eagles will kick off 2025 season vs. Cowboys

Analyzing factors of Carr’s retirement from NFL

Reflecting on Carr’s ‘fascinating’ NFL career

Why timeline of Carr’s shoulder injury is odd

How Saints are approaching QB competition

Licht gets candid on drafting strong personalities

Sports world reacts to first American-born Pope

Latest Clips

Reflecting on Tiger’s 2000 PGA Championship win

Schauffele shares how Callaway helps his putting

LIV Golf stars looking forward to PGA Championship

Wagner tries out 12th hole at Quail Hollow Club

Can Spieth finish career Grand Slam this weekend?

Scheffler details approach to conquer Quail Hollow

Supercross 2025: Salt Lake City biggest moments

Houck might be removed from Red Sox rotation

Projecting Skattebo’s path to fantasy relevance

Cubs’ Ballesteros has major offensive potential

Packers met with Reed’s agent to discuss WR’s role

DeChambeau bringing renewed confidence to PGA

Weathers’ high-upside worth a bench stash

Burger looks like ‘the same guy’ for Rangers

Schauffele: I’m still trying to prove myself

Flagg immediately alters Mavericks’ timeline

Russo: Mavs winning lottery ‘is a little crazy’

Fever could have tough time clearing 31.5 wins

Target Gilgeous-Alexander, Porter Jr. Game 5 props

Pacers pair leads IND-CLE Game 5 player props

Will Potter be able to turn West Ham around?

Arsenal’s first half v. Reds was ‘unacceptable’

Newcastle have ‘momentum’ going into Arsenal match

Celtics are Game 5 favorites despite Tatum injury

NBA draft intrigue starts with Spurs, 76ers

Look past Clark at current price for WNBA MVP bets

Warriors won’t ‘let go of the rope’ in Game 5

Top Premier League highlights from Matchweek 36

Given analyzes the best saves of the PL season

Hicks explains how Callaway helps his game