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Brewers at Cubs - NLDS Game 3 prediction: Odds, expert picks, starting pitchers, betting trends, and stats

The Milwaukee Brewers have clearly been the superior team through the first two games of their National League Division series against the Chicago Cubs. Jackson Chourio and co. have outscored the Cubbies 16-6. After a day off for travel, the scene shifts today to Wrigley Field as Chicago looks to stay alive and keep their championship hopes alive. Quinn Priester is slated to take the mound for Milwaukee against Jameson Taillon for Chicago.

Offense has not been a problem for the Brew Crew. The aforementioned Chourio is hitting .714 through the first two games of the series going 5-7 with nine total bases. Christian Yelich is batting .500 (4-8) and William Contreras is 4-9 (.444).

While Milwaukee seems to be hitting everything thrown at them, the Cubs are struggling to make contact at the plate. Through five playoff games, Chicago has struck out 58 times. Pete Crow-Armstrong is hitting .222 and Kyle Tucker just .176 in the postseason.

Perhaps the friendly confines of Wrigley Field will wake up the bats for the hometown team but lets dive into Game 3 and see what the numbers forecast.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch the first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.

Game details & how to watch Brewers at Cubs - NLDS Game 3

  • Date: Wednesday, October 8, 2025
  • Time: 5:08PM EST
  • Site: Wrigley Field
  • City: Chicago, IL
  • Network/Streaming: TBS

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Brewers at the Cubs - NLDS Game 3

The latest odds as of Wednesday courtesy of DraftKings:

  • Moneyline: Milwaukee Brewers (-102), Chicago Cubs (-119)
  • Spread: Brewers -1.5 (+172)
  • Total: 6.5 runs

Probable starting pitchers for Brewers at Cubs - NLDS Game 3

  • Pitching matchup for October 8, 2025: Quinn Priester vs. Jameson Taillon
    • Brewers: Quinn Priester (Regular Season: 13-3, 3.32 ERA)
      Last outing: 9/26 vs. Cincinnati - 5IP, 3 ER, 9H, 1BB, and 4Ks
    • Cubs: Jameson Taillon (Regular Season: 11-7, 3.68 ERA)
      Last outing: 10/2 vs. San Diego - 4IP, 0 ER, 2H, 0BB, and 4Ks

Rotoworld has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

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Top betting trends & insights to know ahead of Brewers at Cubs - NLDS Game 3

  • Jackson Chourio is 7-13 (.538) in his career against Jameson Taillon
  • Christian Yelich is 13-37 (.351) in his career against Taillon
  • Nico Hoerner is 4-10 (.400) in his career against Quinn Priester
  • Michael Busch is 2-8 with 4 RBIs in his career against Priester

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for today’s NLDS Game 3 between the Brewers and the Cubs

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Wednesday’s game between the Brewers and the Cubs:

  • Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the Milwaukee Brewers at -1.5.
  • Total: NBC Sports Bet is recommending a play on the over on the Game Total of 6.5.

Follow our experts on socials to keep up with all the latest content from the staff:

  • Jay Croucher (@croucherJD)
  • Drew Dinsick (@whale_capper)
  • Vaughn Dalzell (@VmoneySports)
  • Brad Thomas (@MrBradThomas)