Phillies at White Sox Prediction: Odds, expert picks, starting pitchers, betting trends and stats for July 29

Its Tuesday, July 29 and the Phillies (60-46) are in Chicago as their series against the White Sox (39-68) continues.

Jesús Luzardo is slated to take the mound for Philadelphia against Jonathan Cannon for Chicago.

The series opener last night went to the Sox, 6-2. Chicago scored a couple of runs in the third, fourth, and eighth innings. That was more than enough support for Davis Martin to earn his third win of the season.

Lets dive into tonight’s matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch the first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

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Game details & how to watch Phillies at White Sox

• Date: Tuesday, July 29, 2025
• Time: 7:40PM EST
• Site: Rate Field
• City: Chicago, IL
• Network/Streaming: NBCSP, CHSN

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Phillies at the White Sox

The latest odds as of Tuesday:

• Moneyline: Phillies (-206), White Sox (+171)
• Spread: Phillies -1.5
• Total: 8.0 runs

Probable starting pitchers for Phillies at White Sox

• Pitching matchup for July 29, 2025: Jesús Luzardo vs. Jonathan Cannon
  
  • Phillies: Jesús Luzardo (8-5, 4.58 ERA)
    Last outing: July 23 vs. Boston - 10.80 ERA, 6 Earned Runs Allowed, 2 Hits Allowed, 5 Walks, and 7 Strikeouts
  • White Sox: Jonathan Cannon (4-7, 4.48 ERA)
    Last outing: July 23 at Tampa Bay - 10.39 ERA, 5 Earned Runs Allowed, 7 Hits Allowed, 1 Walks, and 9 Strikeouts

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Top betting trends & insights to know ahead of Phillies at White Sox

• The Phillies have won four of the last five games between these clubs
• Chicago’s Jonathan Cannon allowed five earned runs in 4.1 innings in his last start, against the Rays
• Philadelphia starter Jesus Luzardo has a 7.23 ERA through four starts in July
• Kyle Schwarber has 11 home runs in July
• Trea Turner is 0-8 his last two games after a blistering previous four games that saw him pick up 10 hits in 20 ABs

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for tonight’s game between the Phillies and the White Sox

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Tuesday’s game between the Phillies and the White Sox:

• Moneyline: NBC Sports Bet is recommending a play on the Philadelphia Phillies on the Moneyline.
• Spread: NBC Sports Bet is leaning towards a play ATS on the Chicago White Sox at +1.5.
• Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC

Follow our experts on socials to keep up with all the latest content from the staff:

• Jay Croucher (@croucherJD)
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• Vaughn Dalzell (@VmoneySports)
• Brad Thomas (@MrBradThomas)