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Blue Jays at Dodgers - World Series Game 5 prediction: Odds, expert picks, starting pitchers, trends, stats

Vladimir Guerrero Jr. refuses to let Shohei Ohtani and the Dodgers dominate the story of this World Series. The Jays’ slugger led his team to a 6-2 win over Ohtani and co. with a home run and a couple of RBIs to even the World Series at two games apiece.

The first baseman has hit safely in nine straight playoff games and is hitting .419 overall this postseason with seven home runs and 14 runs batted in (62 ABs).

Ohtani was human last night allowing four runs over six innings including Guerrero’s third inning home run. He also went without a hit striking out twice in four trips to the plate.

Game 5 becomes pivotal now for both sides. The pitching matchup is a rematch of Game 1 with Blake Snell taking the ball for the Dodgers and Trey Yesavage on the bump for Toronto.

Lets dive into the numbers from last night and the Series in general and see where we can find an advantage.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch the first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.

Game details & how to watch Blue Jays at Dodgers - World Series Game 5

  • Date: Wednesday, October 29, 2025
  • Time: 8:00PM EST
  • Site: Dodger Stadium
  • City: Los Angeles, CA
  • Network/Streaming: FOX

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for World Series Game 5 - Blue Jays at Dodgers

The latest odds as of Wednesday courtesy of DraftKings:

  • Moneyline: Toronto Blue Jays (+168), Los Angeles Dodgers (-207)
  • Spread: Dodgers -1.5 (-102)
  • Total: 8.0 runs

Probable starting pitchers for Blue Jays at Dodgers - World Series Game 5

  • Pitching matchup for October 29, 2025: Trey Yesavage vs. Blake Snell
    • Blue Jays: Trey Yesavage (1-0, 3.21 ERA)
      Game 1 Results: 4IP, 4H, 2ER, 3BB, 5Ks
      Postseason: 19IP, 9ER, 14H, 10BB, 27Ks
      The 22-year-old Yesavage began this season in Single A Ball.
    • Dodgers: Blake Snell (5-4, 2.35 ERA)
      Game 1 Results: 5IP, 5ER, 8H, 3BB, 4Ks
      Postseason: 26IP, 7ER, 14H, 8BB, 32Ks
      Snell had allowed just 2ER in 3 starts prior to his Game 1 implosion

Rotoworld has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Blue Jays at Dodgers World Series Game 5

  • Alejandro Kirk is 5-7 (.714) in his career against Blake Snell
  • Daulton Varsho and George Springer are the only Jays to have gone yard against Snell
  • Enrique Hernandez and Will Smith each drove in a run in Game 1 against Trey Yesavage
  • Shohei Ohtani was 0-2 (1K) against Yesavage in Game 1

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for tonight’s Game 5 between the Blue Jays and the Dodgers

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Wednesday’s game between the Blue Jays and the Dodgers

  • Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the Toronto Blue Jays at +1.5.
  • Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC Sports.

Follow our experts on socials to keep up with all the latest content from the staff:

  • Jay Croucher (@croucherJD)
  • Drew Dinsick (@whale_capper)
  • Vaughn Dalzell (@VmoneySports)
  • Trysta Krick (@Trysta_Krick)