Nationals at Cardinals Prediction: Odds, expert picks, starting pitchers, betting trends, stats for July 10

It’s Thursday, July 10 and the Nationals (38-54) are in St. Louis to take on the Cardinals (49-44). Michael Soroka is slated to take the mound for Washington against Miles Mikolas for St. Louis.

Washington took Tuesday’s matchup over St. Louis, 8-2, to even up the series. The Nationals were on a four-game losing streak, so that was a much-needed win. The Cardinals are 2-2 in the past four games and 2-6 in the previous eight.

Let’s dive into the matchup and find a sweat or two. We’ve got all the info and analysis you need to know ahead of the game, including the latest info on how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

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Game details & how to watch Nationals at Cardinals

• Date: Thursday, July 10, 2025
• Time: 7:45PM EST
• Site: Busch Stadium
• City: St. Louis, MO
• Network/Streaming: MASN, FDSNMW

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Odds for the Nationals at the Cardinals

The latest odds as of Thursday:

• Moneyline: Nationals (+120), Cardinals (-143)
• Spread: Cardinals -1.5
• Total: 8.0 runs

Probable starting pitchers for Nationals at Cardinals

• Pitching matchup for July 10, 2025: Michael Soroka vs. Miles Mikolas
  
  • Nationals: Michael Soroka, (3-6, 5.40 ERA)
    Last outing: 4.0 Innings Pitched, 7 Earned Runs Allowed, 9 Hits Allowed, 2 Walks, and 6 Strikeouts
  • Cardinals: Miles Mikolas, (4-6, 5.26 ERA)
    Last outing: 6.0 Innings Pitched, 8 Earned Runs Allowed, 10 Hits Allowed, 0 Walks, and 4 Strikeouts

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Expert picks & predictions for tonight’s game between the Nationals and the Cardinals

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Thursday’s game between the Nationals and the Cardinals:

• Moneyline: NBC Sports Bet is recommending a play on the St. Louis Cardinals on the Moneyline.
• Spread: NBC Sports Bet is leaning towards a play ATS on the Washington Nationals at +1.5.
• Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC.

Top betting trends & insights to know ahead of Nationals at Cardinals

• Washington is 0-5 in the last five with Soroka pitching
• Washington is 2-9 in the 11 starts for Soroka this year
• St. Louis is 1-4 in the last five with Mikolas pitching
• The Cardinals have won 3 straight matchups against the Nationals with Miles Mikolas opening
• In his last 5 starts on the mound, Cardinals pitcher Miles Mikolas has an 8.31 ERA
• Each of the Cardinals’ last 5 wins have been by 2+ runs

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

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• Jay Croucher (@croucherJD)
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• Vaughn Dalzell (@VmoneySports)
• Brad Thomas (@MrBradThomas)