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Red Sox at Phillies prediction: Odds, expert picks, starting pitchers, betting trends, and stats for July 23

It’s Wednesday, July 23 and the Red Sox (54-49) are in Philadelphia to take on the Phillies (58-43). Lucas Giolito is slated to take the mound for Boston against Jesús Luzardo for Philadelphia.

The Phillies held the Red Sox to one run and held onto a 4-1 victory to follow up the 3-2 win in extra innings on Monday. Boston is 1-4 in the last five games and scored two or fewer runs in each of the four losses.

Let’s dive into the matchup and find a sweat or two. We’ve got all the info and analysis you need to know ahead of the game, including the latest info on how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.

Game details & how to watch Red Sox at Phillies

  • Date: Wednesday, July 23, 2025
  • Time: 7:05PM EST
  • Site: Citizens Bank Park
  • City: Philadelphia, PA
  • Network/Streaming: ESPN

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Red Sox at the Phillies

The latest odds as of Wednesday:

  • Moneyline: Red Sox (+130), Phillies (-155)
  • Spread: Phillies -1.5
  • Total: 8.0 runs

Probable starting pitchers for Red Sox at Phillies

  • Pitching matchup for July 23, 2025: Lucas Giolito vs. Jesús Luzardo
    • Red Sox: Lucas Giolito, (6-2, 3.59 ERA)
      Last outing: 6.75 ERA, 4 Earned Runs Allowed, 5 Hits Allowed, 2 Walks, and 6 Strikeouts
    • Phillies: Jesús Luzardo, (8-5, 4.29 ERA)
      Last outing: 7.71 ERA, 4 Earned Runs Allowed, 7 Hits Allowed, 2 Walks, and 7 Strikeouts

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Expert picks & predictions for tonight’s game between the Red Sox and the Phillies

Rotoworld Best Bet

Vaughn Dalzell (@VmoneySports) likes the value on Boston to miss the postseason:

“Boston has the third-toughest remaining strength of schedule (.516 winning %). Let’s look at the first 15 games of the second half for Boston:

3 road games at the Cubs (1-2 record)
3 road games at the Phillies (0-2 record)
3 home games vs the Dodgers
3 road games at the Twins
3 home games vs the Astros

That schedule alone could put them behind and make a +105 to -115 bet became -200 to -300 quickly (already -180). During the All-Star break, I played Boston at plus-money to miss the postseason and think it’s still a good bet after losing three of four after the break.”

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Wednesday’s game between the Red Sox and the Phillies:

  • Moneyline: NBC Sports Bet is recommending a play on the Philadelphia Phillies on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the Boston Red Sox at +1.5.
  • Total: NBC Sports Bet is staying away from a play on the Game Total of 8.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC.

Top betting trends & insights to know ahead of Red Sox at Phillies

  • The Phillies have won 3 straight home games against the Red Sox
  • 4 of the Red Sox’s last 5 road games stayed under the Total
  • Boston is 1-4 in the last five games
  • Philly is 1-3 in Luzardo’s last four starts
  • Boston is 3-1 in Giolito’s last four starts

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Follow our experts on socials to keep up with all the latest content from the staff:

  • Jay Croucher (@croucherJD)
  • Drew Dinsick (@whale_capper)
  • Vaughn Dalzell (@VmoneySports)
  • Trysta Krick (@Trysta_Krick)