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Astros at Angels Prediction: Odds, expert picks, starting pitchers, betting trends, and stats for June 20

It’s Friday, June 20, and the Astros (43-32) are in Anaheim to take on the Angels (36-38). Hunter Brown is slated to take the mound for Houston against Yusei Kikuchi for Los Angeles.

The Astros are coming off a 6-4 loss to the Athletics last night despite a decent effort from Colton Gordon. The Astros’ pitcher only gave up two earned runs in 5.0 innings pitched.

With a 7-3 loss, the Los Angeles Angels were unable to sweep the New York Yankees.

Let’s dive into the matchup and find a sweat or two. They have made a slight dent in the Astros’ lead in the AL West. They are now only 6.5 games behind the division leaders.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.

Game details & how to watch Astros at Angels

  • Date: Friday, June 20, 2025
  • Time: 9:38PM EST
  • Site: Angel Stadium
  • City: Anaheim, CA
  • Network/Streaming: FanDuel Sports Home Network, Space City Home Network

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Astros at the Angels

The latest odds as of Friday:

  • Moneyline: Astros (-184), Angels (+154)
  • Spread: Astros -1.5
  • Total: 8.0 runs

Probable starting pitchers for Astros at Angels

  • Pitching matchup for June 20, 2025: Hunter Brown vs. Yusei Kikuchi
    • Astros: Hunter Brown, (8-3, 1.88 ERA)
      Last outing (Minnesota Twins, 6/14): 7.0 Innings Pitched, 2 Earned Runs Allowed, 3 Hits Allowed, 1 Walks, and 12 Strikeouts
    • Angels: Yusei Kikuchi, (2-6, 3.05 ERA)
      Last outing (Baltimore Orioles, 6/15): 5.2 Innings Pitched, 3 Earned Runs Allowed, 7 Hits Allowed, 2 Walks, and 10 Strikeouts

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries, and transactions where you can filter by league, team, positions, and news type!

Top betting trends & insights to know ahead of Astros at Angels

  • The Astros have won 5 of their last 7 divisional matchups
  • The Under is 41-30-4 in Astros’ games this season
  • The Astros have covered the Run Line in 5 of their last 6 road games against the Angels

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for tonight’s game between the Astros and the Angels

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread, and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information, and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Friday’s game between the Astros and the Angels:

  • Moneyline: NBC Sports Bet is recommending a play on the Houston Astros on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the Los Angeles Angels at +1.5.
  • Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC

Follow our experts on socials to keep up with all the latest content from the staff:

  • Jay Croucher (@croucherJD)
  • Drew Dinsick (@whale_capper)
  • Vaughn Dalzell (@VmoneySports)
  • Brad Thomas (@MrBradThomas)