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Eagles vs Bears Odds, expert picks, team and player news, betting trends, and stats

The Chicago Bears (1-1) host the Philadelphia Eagles (2-0) at Soldier Field for Monday Night Football! This game had fireworks around it a week ago, but the hype has popped like a balloon after Caleb Williams was injured the Bears Week 2 loss to the Vikings. The betting line went from Chicago -1.5 to Philadelphia -4.5 — a six-point swing! The Eagles have their own injures on offense to and question surround whether or not Saquon Barkley will play after suffering a neck and shoulder injury against Tennessee.

The Philadelphia offense had the ball for over 75% of the first half against Tennessee yet held a 14-10 lead. Hurts had an up-and-down game. One of his two interceptions was returned 92 yards and set up a touchdown for the Titans, while the other set up the go-ahead field goal for Tennessee in the fourth quarter (20-17). Hurts responded the only way he knows how and marched the Eagles down the field for a nine-play 65-yard touchdown drive with nine seconds remaining. The Eagles narrowly escaped the Titans, 24-20. Saquon Barkley was injured in the win (neck/shoulder) as the Eagles had to use a committee and Dallas Goedert will be out for a few weeks spraining his MCL.

Chicago is dealing with its own injury issues as well, most importantly at the quarterback position. Caleb Williams suffered a hamstring injury in the red zone with a chance to take the lead against the Vikings, then Tyson Bagent ended up in concussion protocol, so the Bears are down to their third-string quarterback, Case Keenum. The 38-year-old hasn’t thrown a regular season pass since 2023, so the Bears game plan will be something to keep an eye on following a 10-3 loss. Chicago ran the ball well with 134 yards on 31 carries (4.3 ypc), but Philadelphia and fellow opponents know more than ever, the Bears will be running the ball early and often.

Let’s dive into the numbers and see if we can’t find an additional sweat or two.

NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates, and of course our predictions and best bets for the game from our staff of experts.

Game details and how to watch Eagles at Bears

· Date: Monday, September 28, 2026
· Time: 8:15 PM ET
· Site: Soldier Field
· City: Chicago, IL
· TV/Streaming: ESPN | ABC

NBC Sports is your home for all the latest updates on this matchup, featuring live odds, player news, expert analysis, and predictions.

Latest Game Odds for Eagles at Bears

The latest odds courtesy of DraftKings:

· Moneyline: Philadelphia Eagles (-218), Chicago Bears (+180)
· Spread: Eagles -4.5
· Total: 41.5

The look ahead spread for this game was Chicago -1.5, so the six-point swing to Philadelphia -4.5 represents the Bears being down to its third-string quarterback. Naturally, the total dipped as well going from 46.5 to 41.5.

NBC Sports Bet Best Bets

Expert picks & predictions for Eagles at Bears

Vaughn Dalzell (@VmoneySports) likes the Under 41.5:

“Chicago’s offense took more than a six-point swing when Caleb Williams went down with an injury and it got worse when Tyson Bagent did as well. With Case Keenum under center, it’s hard seeing Chicago scoring more than 10 points unless the ground game breaks through that nasty Eagles front seven. Philadelphia hasn’t been the most fluid offense either and with Saquon Barkley questionable and Dallas Goedert out, I think the best bet is going to the Under in this matchup. Both of the Eagles first two games have gone Over the total, but the Over cashed on the second to last possession of each.”

Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.

Eagles at Bears betting trends and stats

  • Philadelphia is 0-2 ATS and 2-0 to the Over
  • Chicago is 1-1 ATS and 1-1 on the total
  • Philadelphia is 4-4 ATS in the last eight games as a road favorite and 4-4 on the total
  • Chicago was an NFL-best 3-0 ATS as a home underdog last year
  • Chicago is 7-2-2 ATS as a home underdog since 2023 and 6-5 to the Under
  • Philadelphia is 19-10 ATS following a win since 2024
  • Philadelphia was 8-3 ATS following a win last year, ranking second-best
  • Chicago went 4-2 ATS following a loss last year and is 14-10-3 ATS since 2023 in this spot
  • Chicago is 10-8 to the Under following a loss in the last 18 instances

Quarterback matchup for Eagles at Bears

· Philadelphia: Jalen Hurts – Hurts almost lose the game for the Eagles against the Titans, but he redeemed himself with a game-winning drive. Hurts tossed two picks that led to 10 of 20 points for the Titans, but also responded after both turnovers with leading Philadelphia to a touchdown on each drive. Hurts finished with 264 passing yards, 16 rushing yards, 26-of-3 (70.3%) through the air, and two passing touchdowns to two interceptions. Hurts has been sacked six times through three games and Chicago’s racked up five sacks in that span. If Barkley is out, Chicago might bring the pressure more than usual.

· Chicago: Case Keenum – Caleb Williams suffered a hamstring injury on the potential game-tying or game-winning drive in Week 2’s loss to the Vikings, but it gets worse. Backup QB Tyson Bagent is in five-step concussion protocol, so Chicago may be forced to start its only healthy quarterback on the roster, Case Keenum. This could be a nightmare scenario or season for Chicago pending how long Williams is out for. The 38-year-old Keenum hasn’t thrown a regular season pass since 2023. He played two games for Houston (1-1 record) and tossed three interceptions, 291 yards, and a touchdown.

Eagles at Bears Injury Update

  • Chicago QB Caleb Williams (hamsring) is out
  • Chicago QB Tyson Bagent (concussion) is doubtful
  • Chicago CB Tyrique Stevenson Sr (hamstring) is questionable
  • Philadelphia TE Dallas Goedert (MCL) is out
  • Philadelphia RB Saquon Barley (neck/shoulder) is questionable
  • Philadelphia LB Jonathan Greenard (pectoral strain) is questionable

Rotoworld still has you covered with all the latest and tools for the NFL, including game predictions, player props, futures, and trends!

Follow our experts on socials to keep up with all the latest content from the staff:

  • Jay Croucher (@croucherJD)
  • Drew Dinsick (@whale_capper)
  • Vaughn Dalzell (@VmoneySports)
  • Trysta Krick (@Trysta_Krick)