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Raiders at Commanders prediction: Odds, expert picks, QB matchup, injury update, betting trends, and stats

The Las Vegas Raiders (1-1) on short rest and traveling across the country take the field Sunday in our nation’s capital against the more rested but more banged up Washington Commanders (1-1).

Since last week’s loss on Thursday night to the Packers, Washington has revealed their quarterback is a candidate to miss at least this week’s game. Last season’s Rookie of the Year and MVP candidate Jayden Daniels is “day-to-day” with a knee injury according to Head Coach Dan Quinn. Should the signal-caller be deemed unavailable for Sunday’s game, Marcus Mariota will step under center.

Its a quick turnaround for the Raiders following Monday night’s loss to the Chargers. Pete Carroll’s crew never led and was generally not good in the 20-9 loss to Los Angeles. Geno Smith was the leader of the “not good” team throwing three picks while completing just 24 of 43 passes for 180yds. Vegas totaled a mere 218 yards on the night.

Can Vegas get on track and take advantage of at least a compromised if not absent Jayden Daniels? Lets take a deeper dive into this week’s matchup.

NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates, and of course our predictions and best bets for the game from our staff of experts.

Game Details and How to watch the Las Vegas Raiders at the Washington Commanders live Sunday

  • Date: Sunday, September 21, 2025
  • Time: 1:00PM EST
  • Site: Northwest Stadium
  • City: Landover, MD
  • Network/Streaming: FOX

Want to check out the other games on the NFL schedule this week? We’ve got you covered right here on NBC Sports with all the matchup, venue, game-time and TV/streaming info so you won’t miss any of the action!

Game odds for the Raiders at the Commanders

The latest odds as of Wednesday courtesy of DraftKings:

  • Moneyline: Raiders (+160), Commanders (-192)
  • Spread: Commanders -3.5
  • Total: 44.5 points

This game opened at Commanders -7.0 with the Game Total set at 47.5.

Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule!

Rotoworld has you covered with all the latest betting info & tools for NFL with player news, game predictions, player props, futures, and trends!

Smith 'a little too aggressive' to begin season
Chris Simms and Connor Rogers recap the second game of Monday Night Football where the Los Angeles Chargers defeated the Las Vegas Raiders.

Quarterback Matchup for Las Vegas Raiders at Washington Commanders

  • Raiders Starting QB: Geno Smith
    Last Game: 9/15 vs. Chargers - 24-43 (55.8%), 180yds, 0 TDs, 3 INTs, Sacked 3 times, 5 carries for 20yds
  • Season: 2GP, 48-77 (62.3%), 542yds, 1 TD, 4 INTs, Sacked 7 times, 7 carries for 30yds
  • Commanders Expected Starting QB: Marcus Mariota
    Should he get the call, this will be Mariota’s first appearance this season.
    Last Game: 1/12/24 at Tampa Bay – 0-0 (0.0%), 0yds, 0 TDs, 0 INTs, 1 carry for 2yds
    Jayden Daniels
    Last Game: 9/11 at Green Bay – 24-42 (57.1%), 200yds, 2 TDs, 0 INTs, Sacked 4 times, 7 carries for 17yds
    Season: 2GP, 43-72 (59.7%), 433yds, 3 TDs, 0 INTs, Sacked 7 times, 18 carries for 85yds

Raiders at Commanders team stats, betting trends

  • The Commanders have covered the Spread in their last 3 games at home
  • 6 of the Commanders’ last 8 home games have gone over the Total
  • Through 2 games, rookie Ashton Jeanty is averaging just 2.7yds/carry and has rushed for a total of just 81yds
  • The previously and maybe still disgruntled Jakobi Meyers is leading the Raiders with 14 catches and 165yds

Raiders Player Injuries

  • RG Jackson Powers-Johnson (undisclosed) is listed as questionable for Sunday’s game

Commanders Player Injuries

  • QB Jayden Daniels (knee) is listed as questionable for Sunday’s game
  • WR Noah Brown (groin) is listed as questionable for Sunday’s game
  • TE John Bates (groin) is listed as questionable for Sunday’s game
  • CB Jonathan Jones (undisclosed) was placed on IR Tuesday
  • DE Deatrich Wise Jr. (quad) was placed on IR Monday
  • RB Austin Ekeler (Achilles) was placed on IR Monday

Rotoworld Bet Best Bets

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Best bets our model is projecting for this week’s game between the Raiders and the Commanders:

  • Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the Las Vegas Raiders at +3.5.
  • Total: NBC Sports Bet is recommending a play on the over on the Game Total of 44.0.

Rotoworld has you covered with all the latest betting info & tools for NFL with player news, game predictions, player props, futures, and trends!

Follow our experts on socials to keep up with all the latest content from the staff:

● Jay Croucher (@croucherJD)
● Drew Dinsick (@whale_capper)
● Vaughn Dalzell (@VmoneySports)
● Trysta Krick (@Trista_Krick)