The Jacksonville Jaguars (4-2) and the Los Angeles Rams (4-2) meet at Wembley Stadium Sunday in the final London game of the 2025 NFL season. Among the storylines for this game is pupil vs. mentor as Liam Coen gets his first opportunity as a head coach against his former boss, Sean McVay. Coen spent 4 seasons with the Rams under HC Sean McVay. He was an assistant WR coach (2018-19), an assistant QB coach (2020) and the team’s Offensive Coordinator (2022).
Last weekend the Rams struggled not to beat themselves in the first half before controlling the game in the second 30 minutes and winning in Baltimore, 17-3. After a win over Kansas City the previous week, the Jaguars lost at home to Seattle last Sunday, 20-12.
The Rams are looking for their best 7-game start since 2021 when they started 6-1 and eventually won the Super Bowl. The Jaguars are looking to tie their best 7-game start in the last 15 seasons. They were 5-2 in 2023.
This will be the Jaguars 14th reg. season game in London, the most by any team in the NFL. Jacksonville is 7-6 all-time in London games, including 3-1 since 2023.
Lets take a deeper dive into this final London game of the season and see what the numbers uncover.
NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates, and of course our predictions and best bets for the game from our staff of experts.
Game Details and How to watch the Rams vs. Jaguars live Sunday
- Date: Sunday, October 19, 2025
- Time: 9:30AM EST
- Site: Wembley Stadium
- City: London, UK
- Network/Streaming: NFL Network
Want to check out the other games on the NFL schedule this week? We’ve got you covered right here on NBC Sports with all the matchup, venue, game-time and TV/streaming info so you won’t miss any of the action!
Game odds for the Rams vs. the Jaguars
The latest odds as of Thursday courtesy of DraftKings:
- Moneyline: Los Angeles Rams (-166), Jacksonville Jaguars (+140)
- Spread: Rams -3
- Total: 44.5 points
This game opened at Rams -3.0 with the Game Total set at 46.5.
Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule!
Quarterback Matchup for Los Angeles at Jacksonville
- Rams Starting QB: Matthew Stafford
Last Game: 10/12 at Baltimore - 17-26, 181yds, 1 TD, 0 INTs, Sacked 2 times, 4 carries for 1yd rushing
Season: 6GP, 139-209, 1684yds, 12 TDs, 2 INTs, Sacked 11 times, 15 carries for -3yds rushing - Jaguars Starting QB: Trevor Lawrence
Last Game: 10/12 vs. Seattle - 27-42, 258yds, 2 TDs, 0 INTs, Sacked 7 times, 3 carries for 9yds rushing
Season: 6GP, 129-211, 1324yds, 8 TDs, 5 INTs, Sacked 13 times, 28 carries for 95yds rushing
Rams vs. Jaguars team stats, betting trends
- Betting the Jaguars on the Money Line in all games this season would have shown a 140% return on investment
- The Jaguars have covered in 4 of their last 5 home games
- The Under is 4-1 in the Jaguars’ last 5 home games
- The Rams have won 7 straight games vs AFC teams, the longest active win streak in interconference play
- Rams QB Matthew Stafford leads the NFL with 1,684 pass yds
- With 316 pass yds, Stafford (2021) can join Hall of Famer Kurt Warner (2000-01) as the only players in Rams history to have multiple seasons with 2,000+ pass yds through 7 games
- Jacksonville leads the NFL with 14 takeaways
Rams Player Injuries
- RB Blake Corum (ankle) is questionable for Sunday’s game
- WR Puka Nakua (ankle) is questionable for Sunday’s game
- WR Tutu Atwell (ankle) is questionable for Sunday’s game
- LB Omar Speights (ankle) is questionable for Sunday’s game
- LB Josaiah Stewart (illness) is questionable for Sunday’s game
- TE Colby Parkinson (concussion) is questionable for Sunday’s game
Jaguars Player Injuries
- C Robert Hainsey (hamstring) is questionable for Sunday’s game
- S Eric Murray (neck) is questionable for Sunday’s game
- LB Yasir Abdullah (hamstring) is questionable for Sunday’s game
- LB Devin Lloyd (calf) has been ruled OUT for Sunday’s game
- TE Quintin Morris (groin) has been ruled out for Sunday’s game
Rotoworld Best Bets
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Drew Dinsick (@whale_capper): Los Angeles vs. Jacksonville Game Total UNDER 44.5 (-107)
The London Finale features two ferocious pass rushes and a limited Rams squad who will be without their top receiver. Jags are live to win in this one but the bigger edge here is on the under as my fair is 42.
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Best bets our model is projecting for this week’s game between the Rams and the Jaguars:
- Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
- Spread: NBC Sports Bet is leaning towards a play ATS on the Jacksonville Jaguars at +3.
- Total: NBC Sports Bet is staying away from a play on the Game Total of 45.0.
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● Jay Croucher (@croucherJD)
● Drew Dinsick (@whale_capper)
● Vaughn Dalzell (@VmoneySports)
● Trysta Krick (@Trista_Krick)
