The Buccaneers are off to a strong start at home against the Patriots.
Quarterback Baker Mayfield tossed a 21-yard touchdown to Emeka Egbuka to give Tampa Bay an early 7-0 lead.
The score capped a quick six-play, 65-yard drive.
Mayfield and Egbuka had also connected earlier in the drive for a 24-yard gain that put the Bucs in New England territory.
Egbuka now leads all rookie receivers with six receiving touchdowns. The No. 19 overall pick has recently been dealing with a hamstring injury, but appears healthy on Sunday.