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Vernon Davis on crutches in locker room with ankle injury

Chicago Bears v San Francisco 49ers

SANTA CLARA, CA - SEPTEMBER 14: Tight end Vernon Davis #85 of the San Francisco 49ers gets hit by cornerback Kyle Fuller #23 of the Chicago Bears during the second quarter of their game at Levi’s Stadium on September 14, 2014 in Santa Clara, California. (Photo by Jeff Gross/Getty Images)

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The 49ers left last night’s game against the Bears with more problems than just a come-from-ahead loss.

According to Matt Maiocco of CSNBayArea.com, tight end Vernon Davis missed the last 10 minutes of the game and was on crutches in the locker room with an ankle injury.

Davis came up hobbling after a hit by Bears linebacker Jon Bostic, in which is foot was caught underneath him. On the next play, Colin Kaepernick was picked off throwing to third-string tight end Derek Carrier. Backup Vance McDonald hurt his knee in the first half and was limited in the second half.

Asked about the condition of his Pro Bowl tight end, 49ers coach Jim Harbaugh replied, “I don’t know. I did not talk to Vernon after the game.”

Obviously there will be tests today to determine his status, including a possible MRI.

But given the shaky start of quarterback Colin Kaepernick, having one of his trusted targets missing is a significant problem if only for a short time.