Mannion defended his approach during a Tuesday presser, two days after the Eagles offense — missing DeVonta Smith and Saquon Barkley — sputtered to a loss against the Rams. The Eagles have put Jalen Hurts under center and utilized play action much more than usual this season. It’s a strategy that hasn’t paid off quite yet. Hurts ranks 31st out of 38 qualifying QBs in adjusted yards per attempt on passes from under center; his 18 percent success rate from under center is by far the worst in the NFL. It’s hard to envision brighter days ahead for Hurts if Smith remains sidelined. He’s barely startable in 12-team formats for now.

The injury, sustained during the Bolts’ Week 4 loss to the Seahawks, will cost Slater between four and six weeks, Rapoport said. It’s yet another massive blow for the struggling Chargers offense. Through Week 4 the Chargers rank 30th in ESPN’s pass blocking win rate and fifth in run blocking win rate. Justin Herbert’s weekly prospects take a hit with the oft-injured Slate sidelined, as do the prospects of LA’s pass catchers.

Dealing with a sprained ankle he sustained last week against the Titans, Jackson will sit out at least one game and could miss multiple weeks, according to Rapoport. Tyler Huntley will make his annual start or two (or three) for the Ravens when they take on the Falcons defense, which is allowing the third lowest drop back success rate in the NFL. It’s a downgrade for Mark Andrews and Zay Flowers, though both should be played in 12-team leagues in Week 5. Huntley should be added in all superflex leagues.

Olave found himself with a relatively quiet receiving line in the first half as the Saints struggled to consistently move the football, something that has become far too familiar under head coach Kellen Moore’s tutelage. As has been the case for some time, Olave got going after the break, ending with his third 100-yard game in four tries, now trailing only CeeDee Lamb in receiving yards through the first month of the season. Fantasy managers will want to monitor the electric wide receiver’s practice status in the coming days after he pulled himself out of the game on the team’s final possession with some sort of ailment. If healthy, Olave remains an elite WR1 ahead of a Week 5 meeting with the Vikings.

The Saints mustered just 16 running back carries in the first game without Travis Etienne, gaining just 50 yards on the ground in the blowout loss. The New Orleans offensive line was completely out-classed by the stout Atlanta defensive front. Kamara briefly departed with a knee injury that required two trips to the medical tent but would return to score his second touchdown of the evening in the fourth quarter. Kamara should continue to lead the backfield in the absence of Etienne and suddenly finds himself as an RB2 in fantasy circles ahead of a Week 5 meeting with the Vikings.

Shough and the Saints stayed true to recent form as they quickly fell into a 14-point hole in the first quarter, with the team now averaging an almost eight point deficit at the half since head coach Kellen Moore took over to start the 2025 season. The team was unable to reproduce the second half magic they so frequently muster behind an overmatched offensive line. Shough needed a late touchdown toss to Devaughn Vele with less than two minutes to play to give fantasy managers something of value. Moore and Shough have their work cut out for them with Brian Flores’ relentless defense coming to town in Week 5, where Shough will be on the QB1/2 border in fantasy circles.

Pitts played just one snap on the team’s first two possessions before seeing modest usage the rest of the game. His counting stats were padded in the second half with a 28-yard, catch-and-run reception on a play action pass out of the flat. Pitts isn’t getting the snaps or route participation to return consistent fantasy production and is best left on fantasy benches for as long as Drake London remains healthy. That won’t change ahead of a Week 5 meeting with the Ravens.

London turned in his second consecutive usable fantasy week with Michael Penix under center. The low volume can primarily be attributed to just 20 Penix pass attempts in a game Bijan Robinson and Brian Robinson combined for 207 yards and five touchdowns on the ground on 33 carries. London could be tasked with more volume when the Falcons host the Ravens in Week 5, for which he will remain an unquestioned WR1 in fantasy circles.

Week 4 marked Robinson’s second consecutive game going over 100 yards with two touchdowns on the ground, this time aided by a 59-yard touchdown run on his first touch of the game. The Falcons tied a franchise record with five rushing scores, with backfield mate Brian Robinson adding three to the two of Bijan. The return of quarterback Michael Penix has given the Falcons the threat of passing after dropping their first two games of the season behind suboptimal play from the position, and nobody has benefited more from reduced numbers in the box than Robinson. He’ll look to keep the momentum going as a top-tier RB1 when the Falcons host the Ravens in Week 5.

Barkley departed the team’s Week 4 loss to the Rams in the second quarter and did not return, with Ian Rapoport relaying that the team views him as “week-to-week,” for the time being. Rapoport added that the team does not view the injury as a long-term issue. Regardless, Barkley appears set to miss multiple games with the soft tissue injury, leaving the team paper thin at running back after backup Tank Bigsby inured a core muscle that requires surgery. Will Shipley is the only other back currently on the active roster, while Dameon Pierce, Carson Steele, and Jaydon Blue are with the team on the practice squad. Shipley warrants a waiver addition while managers in deeper leagues can consider taking an early flier on Blue.