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Eagles vs. Commanders prediction: Odds, expert picks, QB matchup, injury update, betting trends, and stats

The Philadelphia Eagles (9-5) have a chance to clinch their second consecutive NFC East division title Saturday in Landover, MD when they take on the Washington Commanders (4-10).

A win by the Eagles would mark the first time since 2004 that an NFC East team repeated as division champs. The Eagles won their second consecutive division crown that season.

The Eagles looked to have regained their swagger last week in a dominant 31-0 win over the hapless Las Vegas Raiders. The Philly defense held the Raiders to just 75 Total Yards. Vegas ran 42 plays and gained just 75 yards. Ouch! Jalen Hurts threw three touchdowns including a pair to Dallas Goedert to pace the Eagles’ attack on offense.

The Commanders’ season has been a disappointment. Much of that revolves around QB Jayden Daniels consistently being sidelined due to a variety of injuries the latest of which (elbow) is season-ending. As a result, veteran Marcus Mariota will be under center Saturday. He was 10-19 for 211 yards in last weekend’s 29-21 win over the Giants. Jacory Croskey-Merritt led the ground assault gaining 96 yards on 18 carries.

Lets take a deeper dive into this week’s NFC East showdown between the Eagles and the Commanders.

NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates courtesy of Rotoworld, and of course our predictions and best bets for the game from our staff of experts.

Game Details and How to watch the Eagles vs. Commanders live Saturday

  • Date: Saturday, December 20, 2025
  • Time: 5:00PM EST
  • Site: Northwest Stadium
  • City: Landover, MD
  • Network/Streaming: FOX

Want to check out the other games on the NFL schedule this week? We’ve got you covered at NBC Sports with all the matchup, venue, game-time and TV/streaming info so you won’t miss any of the action!

Game Odds: Eagles at Commanders

The latest odds as of Tuesday courtesy of DraftKings:

  • Moneyline: Philadelphia Eagles (-310), Washington Commanders (+250)
  • Spread: Eagles -6.5
  • Total: 44.5 points

This game opened at Eagles -5.5 with the Game Total set at 44.5.

Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule!

Quarterback Matchup for Philadelphia at Washington

  • Eagles Starting QB: Jalen Hurts
    Last Game: 12/14 vs. Las Vegas - 12-15, 175yds, 3TDs, 0INTs, Sacked 1 time, 7 carries for 39yds rushing
    Season: 14GP, 259-397, 2929yds, 22TDs, 6INTs, Sacked 29 times, 95 carries for 376yds rushing
  • Commanders Starting QB: Marcus Mariota
    Last Game: 12/14 at Giants - 10-19, 211yds, 1TD, 0INTs, Sacked 2 times, 10 carries for 43yds rushing
    Season: 10GP, 132-213, 1600yds, 10TDs, 7INTs, Sacked 15 times, 49 carries for 298yds rushing
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Eagles at Commanders: Team Stats and Betting Trends

  • The Commanders are 5-9 ATS this season
  • The Eagles are 8-6 ATS this season
  • The OVER has cashed in 7 of the Commanders’ 14 games this season (7-6-1)
  • The OVER has cashed in 5 of the Eagles’ 14 games this season (5-9)

Eagles Player Injuries

  • RT Lane Johnson (foot) is listed as questionable for Saturday’s game
  • DE Jalen Carter (shoulder) is listed as questionable for Saturday’s game
  • OT Cameron Williams (shoulder) is eligible to be activated off the IR.

Commanders Player Injuries

  • QB Jayden Daniels (elbow) has been declared OUT for Saturday’s game.
  • LT Laremy Tunsil (oblique) is listed as questionable for Saturday’s game
  • RB Chris Rodriguez Jr. (groin) is listed as questionable for Saturday’s game
  • DT Eddie Goldman (concussion) is listed as questionable for Saturday’s game
  • DE Drake Jackson (knee) is listed as questionable for Saturday’s game
  • CB Jonathan Jones (undisclosed) is listed as questionable for Saturday’s game
  • TE Colson Yankoff (ankle) is listed as questionable for Saturday’s game
  • WR Noah Brown (rib) has been placed on the IR and is OUT for Saturday’s game

Rotoworld Best Bets

Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.

Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Best bets our model is projecting for this week’s game between the Eagles and the Commanders

  • Moneyline: Rotoworld Bet is staying away from a play on the Moneyline.
  • Spread: Rotoworld Bet is leaning towards a play ATS on the Philadelphia Eagles -6.5.
  • Total: Rotoworld Bet is recommending a play on the UNDER on the Game Total of 44.5.

Rotoworld has you covered with all the latest betting info & tools for NFL with player news, game predictions, player props, futures, and trends!

Follow our experts on socials to keep up with all the latest content from the staff:

● Jay Croucher (@croucherJD)
● Drew Dinsick (@whale_capper)
● Vaughn Dalzell (@VmoneySports)
● Trysta Krick (@Trista_Krick)