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  • SF Wide Receiver #86
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    KhaDarel Hodge (knee) did not practice Wednesday.

    This is a low blow, even for the subsation. Hodge began the year on San Francisco’s practice squad but was promoted to the active roster when De’Zhaun Stribling went down with an ankle injury. He wound up running 45 percent of the routes in Week 3 but was not targeted once. With Mike Evans also banged up, Jacob Cowing and Jordan Watkins could be in line for more work this week.
  • SF Wide Receiver #17
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    Jordan Watkins caught both of his targets for 60 yards in the 49ers’ Week 3 win over the Cardinals.

    Watkins saw increased opportunity with Mike Evans (rib) exiting in the second quarter. He caught a pair of long targets from Purdy despite KhaDarel Hodge and Jacob Cowing beating the 24-year-old in snaps. Watkins could certainly be on the fantasy radar if Evans misses an extended period of time.
  • SF Running Back #29
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    49ers declared RB Jordan James inactive for Week 1 against the Rams.

    James has officially lost the backup job to rookie RB Kaelon Black, who should be safely stashed on fantasy benches before kickoff. The 49ers also declared QB Kurtis Rourke, CB Ephesians Prysock, WR Jordan Watkins, LB Tatum Bethune and OT Enrique Cruz inactive for Week 1 against the Rams.
  • SF Wide Receiver #19
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    49ers WR Deebo Samuel will take over “a portion” of the Z-receiver role, while also contributing as a “wide back.”

    The Athletic’s Matt Barrows notes that at 30 years old, Samuel is “not going to be close to an every-down player.” 49ers WRs Jordan Watkins and Jacob Cowing are competing to be Samuel’s backup, though neither player will be reliable in fantasy. Samuel may also struggle to return FLEX value at this point in his career.
  • SF Wide Receiver #17
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    49ers head coach Kyle Shanahan said he is excited by the work WR Jordan Watkins and WR Jacob Cowing have been putting in this offseason.

    Watkins drew positive reviews as a rookie last summer, but September ankle and calf injuries stunted his development, pushing him to the bottom of the depth chart. Cowing’s second NFL season was derailed by a recurring hamstring strain. The Athletic’s Matt Barrows listed him as a standout at Thursday’s practice, but he caught just four passes as a 2024 rookie. Expectations for him must be tempered. Watkins is worth monitoring for deep-league managers.
  • SF Wide Receiver #15
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    49ers WR Jauan Jennings (ankle/ribs/shoulder) was removed from the injury report and will play in Week 7 against the Falcons.

    Jennings is very difficult to trust after last week’s meltdown. He was limited twice to begin the week, and we do not yet know his Friday participation level. At this point, the big-bodied wide receiver can only be viewed as a boom-bust WR4/FLEX option. If and when he resumes practicing in full consistently, we will be able to upgrade him to WR3 status. 49ers rookie WR Jordan Watkins (calf) is also expected to play this weekend.
  • SF Wide Receiver #17
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    49ers coach Kyle Shanahan said Jordan Watkins (calf) is expected to resume practicing this week.

    We were just thinking the 49ers wideout projections needed another variable to deal with. Watkins briefly wowed in training camp before dealing with a high-ankle sprain and later this calf issue. It’s possible he cuts into some veteran playing time if the 49ers wideout room remains unsettled, but he’s not someone to rush and pick up in re-draft leagues without seeing some real signs of fantasy life.
  • SF Quarterback #13
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    49ers ruled out QB Brock Purdy (toe) for Week 6 against the Buccaneers.

    Purdy remained sidelined all week, as did WR Ricky Pearsall, who is dealing with a PCL sprain in his knee. Just eight days ago, NFL Network’s Ian Rapoport reported that Purdy is considered week-to-week, so the starting quarterback’s absence is hardly surprising. Hopefully, Purdy can remain setback-free and return for the 49ers’ Week 7 game against the Falcons, though that outcome should not be viewed as guaranteed. The 49ers also ruled out WR Jordan Watkins (calf), DL Kevin Givens (pectoral) and EDGE Yetur Gross-Matos (knee/hamstring).
  • SF Quarterback #10
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    49ers QB Mac Jones (knee) is questionable for Week 4 against the Jaguars.

    49ers starting QB Brock Purdy (toe/left shoulder) has been cleared to play, so Jones has been put back into the No. 2 spot. He played admirably in his two starts, completing 53-of-80 passes for 563 yards, four touchdowns and one interception and rushing seven times for five yards despite aggravating a summer PCL sprain in Week 3. For fantasy managers in two-quarterback leagues with no one better to stash, he can be left on the bench this week to see how Purdy’s health holds up. For everyone else, he can be dropped. The 49ers also ruled out WR Jordan Watkins (calf) and DT CJ West (thumb). FB Kyle Juszczyk passed the NFL’s concussion protocol and will be active for Week 4 against the Jaguars.
  • SF Wide Receiver #17
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    49ers head coach Kyle Shanahan said WR Jordan Watkins (calf) is a candidate for injured reserve.

    Watkins is expected to miss three or four weeks after injuring his calf on Thursday. The rookie wide receiver cannot catch a break. He was considered a candidate to assume Nos. 3 or 4 wide receivers duties at one point in training camp, but his progress was derailed by an ankle injury. Having successfully rehabbed that, he is unfortunately now dealing with a new issue.

NFL Highlights

Judkins' injury puts Sampson on fantasy radar
Kyle Dvorchak breaks down Quinshon Judkins’ uncertain Week 6 status and explains why Dylan Sampson could emerge as a risky fantasy flex option if activated.