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Cardinals at Dodgers Prediction: Odds, expert picks, starting pitchers, betting trends and stats for August 6

Its Wednesday, August 6 and the Cardinals (57-57) are in Los Angeles to take on the Dodgers (65-48). Matthew Liberatore is slated to take the mound for St. Louis against Shohei Ohtani for Los Angeles.

The Dodgers dominated Tuesday night’s meeting 12-6 to even up the series as Max Muncy and Teoscar Hernandez both homered twice. Los Angeles is 5-5 in the last 10 games, while St. Louis is 3-7 in theirs, so neither has played great recently.

Lets dive into the matchup and find a sweat or two. We’ve got all the info and analysis you need to know ahead of the game, including the latest info on how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.

Game details & how to watch Cardinals at Dodgers

  • Date: Wednesday, August 6, 2025
  • Time: 4:10PM EST
  • Site: Dodger Stadium
  • City: Los Angeles, CA
  • Network/Streaming: FDSNMW, SNLA, MLBN

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Cardinals at the Dodgers

The latest odds as of Wednesday:

  • Moneyline: Cardinals (+168), Dodgers (-202)
  • Spread: Dodgers -1.5
  • Total: 9.0 runs

Probable starting pitchers for Cardinals at Dodgers

  • Pitching matchup for August 6, 2025: Matthew Liberatore vs. Shohei Ohtani
    • Cardinals: Matthew Liberatore, (6-9, 3.96 ERA)
      Last outing: 2.08 ERA, 1 Earned Runs Allowed, 4 Hits Allowed, 2 Walks, and 1 Strikeouts
    • Dodgers: Shohei Ohtani, (0-0, 2.40 ERA)
      Last outing: 0.00 ERA, 0 Earned Runs Allowed, 0 Hits Allowed, 1 Walks, and 2 Strikeouts

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Expert picks & predictions for tonight’s game between the Cardinals and the Dodgers

Rotoworld Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Wednesday’s game between the Cardinals and the Dodgers:

  • Moneyline: NBC Sports Bet is recommending a play on the Los Angeles Dodgers on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the St. Louis Cardinals at +1.5.
  • Total: NBC Sports Bet is recommending a play on the under on the Game Total of 9.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC.

Top betting trends & insights to know ahead of Cardinals at Dodgers

  • The Dodgers are 5-5 in the last 10 games
  • The Cardinals are 3-7 in the last 10 games
  • The Cardinals have lost 13 of their last 20 games
  • 11 of the Dodgers’ last 13 games (85%) have stayed under the Total
  • The Dodgers have failed to cover the Run Line in 3 straight home games

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Follow our experts on socials to keep up with all the latest content from the staff:

  • Jay Croucher (@croucherJD)
  • Drew Dinsick (@whale_capper)
  • Vaughn Dalzell (@VmoneySports)
  • Trysta Krick (@Trysta_Krick)