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Mets at Diamondbacks prediction: Odds, expert picks, starting pitchers, betting trends, and stats for May 5

It’s Monday, May 5, and the Mets (22-13) are in Phoenix to take on the Diamondbacks (18-16). Griffin Canning is slated to take the mound for New York against Ryne Nelson for Arizona.

New York is coming off two losses yesterday in a double-header with St. Louis and travels to Arizona to take on the DBacks, which sets up Arizona well off an 11-9 thrilling home win over Philadelphia last night.

Let’s dive into the matchup and find a sweat or two. We’ve got all the info and analysis you need to know ahead of the game, including the latest info on how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.

Game details & how to watch Mets at Diamondbacks

  • Date: Monday, May 5, 2025
  • Time: 9:40 PM EST
  • Site: Chase Field
  • City: Phoenix, AZ
  • Network/Streaming: SNY, ARID

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Mets at the Diamondbacks

The latest odds as of Monday:

  • Moneyline: Mets (-115), Diamondbacks (-105)
  • Spread: Mets -1.5
  • Total: 9.0 runs

Probable starting pitchers for Mets at Diamondbacks

  • Pitching matchup for May 5, 2025: Griffin Canning vs. Ryne Nelson
    • Mets: Griffin Canning, (4-1, 2.61 ERA)
      Last outing: Innings Pitched, Earned Runs Allowed, Hits Allowed, Walks, and Strikeouts
    • Diamondbacks: Ryne Nelson, (1-0, 5.82 ERA)
      Last outing: 4.0 Innings Pitched, 0 Earned Runs Allowed, 0 Hits Allowed, 2 Walks, and 3 Strikeouts

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Expert picks & predictions for tonight’s game between the Mets and the Diamondbacks

Rotoworld Best Bet

Vaughn Dalzell (@VmoneySports) leans Arizona to beat New York:

“Arizona is 1-6 when Nelson pitches this season compared to 17-10 when he does not, while New York is 5-1 when Canning pitches, including five consecutive wins. The obvious would point to the value on the visiting Mets, but having played a double-header yesterday, losing both, and going on the road again isn’t a recipe I’d be willing to bet into. I lean toward the short-home underdog in Arizona.”

Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.

Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Monday’s game between the Mets and the Diamondbacks:

  • Moneyline: NBC Sports Bet is recommending a play on the New York Mets on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the Arizona Diamondbacks at +1.5.
  • Total: NBC Sports Bet is recommending a play on the over on the Game Total of 9.0.

Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC

Top betting trends & insights to know ahead of Mets at Diamondbacks

  • The Mets have won seven of their last 10 games against teams with winning records
  • The Mets’ last three games have gone over the total
  • The Diamondbacks have scored at least four runs in seven of the last eight home games

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Follow our experts on socials to keep up with all the latest content from the staff:

  • Jay Croucher (@croucherJD)
  • Drew Dinsick (@whale_capper)
  • Vaughn Dalzell (@VmoneySports)
  • Brad Thomas (@MrBradThomas)