Skip navigation
Favorites
Sign up to follow your favorites on all your devices.
Sign up
Odds by

Broncos at Eagles prediction: Odds, expert picks, QB matchup, injury update, betting trends, and stats

Sunday in Philadelphia, the undefeated Eagles (4-0) host the Denver Broncos (2-2). It is a matchup that will be a measuring stick for each club and specifically each’s offense.

To date, the Eagles have been stout overall defensively (allowing 22pts/gm) but clunky (yet efficient) on offense. Jalen Hurts is averaging just 138 yards passing (last in the league) and Saquon Barkley and his fellow backs are averaging just 3.5 yards per carry (fourth-worst in the NFL). But all is not doom and gloom in the City of Brotherly Love as the Eagles are averaging 27 points per game (7th in the NFL).

Meanwhile, the Broncos are even stingier on defense the Philly with opponents averaging a mere 16.8 points per game. Denver has allowed opponents to cross the goal line just four times through their first four games. The offense, though, has yet to reach the heights imagined by Head Coach Sean Payton. Bo Nix is averaging a little over 211 yards passing per game and J.K. Dobbins is coming off his first 100-yard game rushing as a member of the Broncos. The hope in Denver is the offense is starting to get on track and will improve on its current average of 22 points per game.

Specific to Sunday’s game, if Denver wants to leave Lincoln Financial Field with a win, they’ll need to limit mistakes and impose their will early. Expect a physical, tightly contested affair in what could well end up being a statement game for these teams.

Last week, the Broncos throttled an undermanned Cincinnati squad, 28-3. The Eagles outlasted the Buccaneers in Tampa Bay, 31-25.

Lets focus on Sunday and take a deeper dive into this week’s matchup.

NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates, and of course our predictions and best bets for the game from our staff of experts.

Game Details and How to watch the Broncos at the Eagles live Sunday

  • Date: Sunday, October 5, 2025
  • Time: 1:00PM EST
  • Site: Lincoln Financial Field
  • City: Philadelphia, PA
  • Network/Streaming: CBS

Want to check out the other games on the NFL schedule this week? We’ve got you covered right here on NBC Sports with all the matchup, venue, game-time and TV/streaming info so you won’t miss any of the action!

Game odds for the Broncos at the Eagles

The latest odds as of Wednesday courtesy of DraftKings:

  • Moneyline: Denver Broncos (+164), Philadelphia Eagles (-198)
  • Spread: Eagles -3.5
  • Total: 43.5 points

This game opened at Eagles -5.5 with the Game Total set at 43.5.

Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule!

Quarterback Matchup for Denver at Philadelphia

  • Broncos Expected Starting QB: Bo Nix
    Last Game: 9/29 vs. Cincinnati - 29-42, 326yds, 2 TDs, 1 INT, Was not Sacked, 6 carries for 7yds
    Season: 4GP, 90-137, 861yds, 7 TDs, 4 INTs, Sacked 3 times, 25 carries for 78yds
  • Eagles Expected Starting QB: Jalen Hurts
    Last Game: 9/28 at Tampa Bay - 15-24, 130yds, 2 TDs, 0 INTs, Sacked 2 times, 9 carries for 62yds
    Season: 4GP, 70-101, 609yds, 5 TDs, 0 INTs, Sacked 9 times, 41 carries for 179yds

Broncos at Eagles team stats, betting trends

  • The Eagles have won 17 of their last 20 games at home, while the Broncos have lost 3 straight on the road
  • The Eagles have covered in 4 of their last 5 games
  • The Eagles’ last 3 games have gone over the Total
  • The Broncos’ Game Totals are 1-3 to the OVER this season
  • The Broncos are 2-2 ATS this season
Sirianni addresses Brown's tweet, lackluster stats
Mike Florio and Devin McCourty explain why Nick Sirianni said exactly what they’d expect him to in a situation like this but why the Eagles have a legitimate problem with A.J. Brown.

Broncos Player Injuries

  • The Broncos are reporting no new injuries this week

Eagles Player Injuries

  • RT Lane Johnson (shoulder) is listed as questionable for Sunday’s game
  • DE Jalen Carter (shoulder) is listed as questionable for Sunday’s game
  • CB Adoree’ Jackson (groin) is listed as questionable for Sunday’s game
  • LB Nakobe Dean (knee) was designated to return from the IR Wednesday but is unlikely to play Sunday
  • LS Charley Hughlett (abdomen) was placed on the IR Tuesday

Rotoworld Bet Best Bets

Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.

Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Best bets our model is projecting for this week’s game between the Broncos and the Eagles:

  • Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the Philadelphia Eagles at -4.5.
  • Total: NBC Sports Bet is recommending a play on the under on the Game Total of 43.0.

Rotoworld has you covered with all the latest betting info & tools for NFL with player news, game predictions, player props, futures, and trends!

Follow our experts on socials to keep up with all the latest content from the staff:

● Jay Croucher (@croucherJD)
● Drew Dinsick (@whale_capper)
● Vaughn Dalzell (@VmoneySports)
● Trysta Krick (@Trista_Krick)