Following last week’s debacle at Carolina, the Dolphins (1-4) are at a crossroads (or maybe they will realize its a dead end) as they prepare to take on the Los Angeles Chargers (3-2) in Miami Sunday afternoon. Mike McDaniel needs this win to maintain whatever hold he still has on his locker room, and his team needs a win to stay at least on the perimeter of the playoff chase in the AFC.
On the other sideline sit the banged-up Chargers. Flying across the country to suit up against arguably one of the worst teams in the league seems like a walk in the park for Los Angeles. Is this a trap game for the Chargers? Doubtful as Jim Harbaugh knows this game is vital to the Chargers. Yes, LA’s O-line is beat up but opposing running backs feast on the Miami defense. The Dolphins’ unit on that side of the ball does not tackle well. They get minimal push off the line. Harbaugh will look to attack and expose those issues.
Whose will wins out - the team that simply has to be desperate and is at home OR the team flying cross country for an early afternoon game but with more talent and a better coach?
Lets dive into the numbers and see what they tell us as we prepare for this matchup in South Florida.
NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates, and of course our predictions and best bets for the game from our staff of experts.
Game Details and How to watch the Chargers vs. Dolphins live Sunday
- Date: Sunday, October 12, 2025
- Time: 1:00PM EST
- Site: Hard Rock Stadium
- City: Miami Gardens, FL
- Network/Streaming: CBS
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Game odds for the Chargers at the Dolphins
The latest odds as of Sunday courtesy of DraftKings:
- Moneyline: Los Angeles Chargers (-218), Miami Dolphins (+180)
- Spread: Chargers -4.5
- Total: 44.5 points
This game opened at Chargers -5.5 with the Game Total set at 44.5.
Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule!
Quarterback Matchup for Los Angeles at Miami
- Chargers Expected Starting QB: Justin Herbert
Last Game: 10/5 vs. Washington - 22-29, 166yds, 1 TD, 1 INT, Sacked 4 times, 4 carries for 60yds
Season: 5GP, 117-178, 1229yds, 8 TDs, 4 INTs, Sacked 16 times, 23 carries for 153yds - Dolphins Expected Starting QB: Tua Tagovailoa
Last Game: 10/5 at Carolina - 27-36, 256yds, 3 TDs, 0 INTs, Sacked 3 times, 1 carry for 5yds
Season: 5GP, 106-150, 1008yds, 10 TDs, 4 INTs, Sacked 11 times, 7 carries for 28yds
Chargers at Dolphins team stats, betting trends
- The Chargers have won 11 of their last 13 games against teams on the East Coast
- The Dolphins went 7-10 against the spread last season
- The Chargers’ last 4 games against AFC teams have gone over the Total
- Game Totals in Chargers’ games are 1-4 to the OVER this season
- Game Totals in Dolphins’ games are 4-1 to the OVER this season
Chargers Player Injuries
- WR Quentin Johnson (hamstring) is questionable for Sunday’s game
- WR Derius Davis (knee) is questionable for Sunday’s game
- FB Scott Matlock (ankle) is questionable for Sunday’s game
- LT Joe Alt (ankle) is questionable for Sunday’s game
- RT Trey Pimpkins III (undisclosed) is questionable for Sunday’s game
- G Jamaree Salyer (undisclosed) is questionable for Sunday’s game
- DE Da’Shawn Hand (groin) is questionable for Sunday’s game
LB Bud Dupree (undisclosed) is questionable for Sunday’s game
Dolphins Player Injuries
- TE Darren Waller (hip) is questionable for Sunday’s game
- CB Storm Duck (ankle) is questionable for Sunday’s game
- WR Cedrick Wilson Jr (knee) is questionable for Sunday’s game
- S Elijah Campbell (quad) has been declared OUT of Sunday’s game
- LB Tyrel Dodson (concussion) has been declared out of Sunday’s game
Rotoworld Bet Best Bets
Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.
Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Best bets our model is projecting for this week’s game between the Chargers and the Dolphins:
- Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
- Spread: NBC Sports Bet is leaning towards a play ATS on the Miami Dolphins at +4.5.
- Total: NBC Sports Bet is leaning towards a play on the over on the Game Total of 44.5.
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