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Giants vs. Lions - Dart OUT - prediction: Odds, expert picks, QB matchup, injury update, trends, and stats

The struggling New York Giants (2-9) will take the field this weekend WITHOUT Jaxson Dart Sunday in Motown against Jared Goff and the Detroit Lions (6-4).

Last week’s loss in Philly to the Eagles dropped the Lions to eighth place overall in the NFC and 1/2 game out of the playoffs. With games the next three weeks against the Packers, the Cowboys, and the Rams this game is a must win for the home team. The offense continues to be feast or famine even with Dan Campbell now calling the plays. The Lions scored 44 two weeks ago in his debut as the play-caller but just nine last week.

The Giants’ offense was bad before injuries to Jaxson Dart (concussion), Malik Nabers (knee), and Cam Skattebo (ankle) and for obvious reasons somehow worse without them. Dart has been declared OUT for Sunday’s game and so Jameis Winston gets the start under center. will be back under center this week. The veteran started last weekend and, true to form, threw an interception late in the fourth quarter to snuff out a potential game-tying drive.

Matchup to Watch: Jahmyr Gibbs and David Montgomery vs. New York Giants’ Run Defense
The Lions’ backfield has rushed for just over 1300 yards this season / 4.6 yards per carry. The Giants’ run defense is the worst in the league having allowed 1650 yards / 5.5 yards per carry.

Lets take a deeper dive into this week’s matchup between the Giants and the Lions.

NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates courtesy of Rotoworld, and of course our predictions and best bets for the game from our staff of experts.

Game Details and How to watch the Giants vs. Lions live Sunday

  • Date: Sunday, November 23, 2025
  • Time: 1:00PM EST
  • Site: Ford Field
  • City: Detroit, MI
  • Network/Streaming: FOX

Want to check out the other games on the NFL schedule this week? We’ve got you covered at NBCSports.com with all the matchup, venue, game-time and TV/streaming info so you won’t miss any of the action!

Game odds for the Giants at the Lions

The latest odds as of Tuesday courtesy of DraftKings:

  • Moneyline: New York Giants (+550), Detroit Lions (-800)
  • Spread: Lions -12.5
  • Total: 50.5 points

This game opened at Lions -10.5 with the Game Total set at 49.5.

Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule!

NFL Week 12 Preview: Giants vs. Lions
Mike Florio and Chris Simms preview the Detroit Lions hosting the New York Giants in Week 12.

Quarterback Matchup for New York at Detroit

  • Giants Starting QB: Jameis Winston
    Last and Only Game: 11/16 at Green Bay - 19-29, 201yds, 0TDs, 1INT, Sacked 2 times, 3 carries for 10yds rushing
  • Lions Starting QB: Jared Goff
    Last Game: 11/16 at Philadelphia - 14-37, 255yds, 1TD, 1INT, Sacked 2 times, 1 carry for -1yd rushing
    Season: 10GP, 216-310, 2490yds, 21TDs, 4INTs, Sacked 20 times, 12 carries for 22yds rushing

Giants at Lions team stats, betting trends

  • The Giants have lost 11 straight road games
  • The Lions are 8-2 against the spread in their last 10 games as a favorite
  • The OVER has cashed in 6 of the Giants’ 11 games (6-5)
  • The OVER has cashed 5 times in the Lions’ 10 games (5-5)
  • The Giants are 6-5 ATS this season
  • The Lions are 5-5 ATS this season

Giants Player Injuries

  • QB Jaxson Dart (concussion) is questionable for Sunday’s game
  • LB Kayvon Thibodeaux (shoulder) is questionable for Sunday’s game
  • WR Darius Slayton (hamstring) is questionable for Sunday’s game
  • S Tyler Nubin (neck) is questionable for Sunday’s game
  • DT Rakeem Nunez-Roches (toe) is questionable for Sunday’s game
  • CB Paulson Adebo (undisclosed) is questionable for Sunday’s game
  • DE Chauncey Golston (undisclosed) is questionable for Sunday’s game

Lions Player Injuries

  • CB Terrion Arnold (concussion) is questionable for Sunday’s game
  • S Kerby Joseph (knee) is questionable for Sunday’s game
  • WR Kalif Raymond (undisclosed) is questionable for Sunday’s game
  • TE Sam LaPorta (back) was placed on the IR Saturday and is OUT for Sunday’s game
  • G Miles Frazier (knee) is eligible to be activated off the IR but has not yet been activated

Rotoworld Best Bets

Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.

Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Best bets our model is projecting for this week’s game between the Giants and the Lions

  • Moneyline: NBC Sports Bet is recommending a play on the New York Giants on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the New York Giants at +10.5.
  • Total: NBC Sports Bet is recommending a play on the UNDER on the Game Total of 49.5.

Rotoworld has you covered with all the latest betting info & tools for NFL with player news, game predictions, player props, futures, and trends!

Follow our experts on socials to keep up with all the latest content from the staff:

● Jay Croucher (@croucherJD)
● Drew Dinsick (@whale_capper)
● Vaughn Dalzell (@VmoneySports)
● Trysta Krick (@Trista_Krick)